School of Population Health and School of Psychology, University of Queensland
Robert S. Ware
School of Population Health, University of Queensland
Christina Lee
School of Psychology, University of Queensland;
Acknowledgement: The Australian Longitudinal Study on Women’s Health is conducted by a team of researchers from the Universities of Queensland and Newcastle, and funded by the Australian Government Department of Health. This analysis was funded by an Australian Research Council Discovery Project Grant to the third author (DP120100167).
Mental health problems appear to be most common during adolescence and early adulthood (e.g.,
This article addresses longitudinal trajectories of mental health problems among a national cohort of young Australian women. Issues concerning mental health in Australia are similar to those in other developed democracies. A recent national survey shows that approximately 45% of Australians will meet criteria for a mental disorder at some stage in their lives, with 20% meeting criteria in any 12-month period. Women are more likely than men to be diagnosed with mental disorders (although men have higher rates of substance abuse), and rates peak in early adulthood and decline with age. Being unpartnered, unemployed, with limited education, or otherwise socially disadvantaged is associated with greater risk of mental disorder, as are smoking, physical inactivity, obesity, and physical illness or disability (
In this article, we take a broad population-health approach to mental health. Although we do not question the value of intensive, smaller-scale, research and intervention with individuals with clinical psychiatric disorders, we adopt the classic epidemiological approach of
Many psychological theorists assume that mental health problems that emerge in adolescence or early adulthood will tend to persist. For example,
Although poor mental health in early adulthood has been shown to be a strong individual predictor of persistent or recurrent mental health problems, population-based research supports the view that this is not inevitable: Up to 50% of people experiencing a first episode of major depression will not experience a recurrence (e.g.,
Numerous longitudinal studies have examined patterns of both clinical and subclinical indicators of poor mental health over time (e.g.,
Research suggests that young people with recurring poor mental health differ from those with nonrecurring poor mental health and from those with ongoing good mental health (
In this analysis, we use trajectory-based modeling of longitudinal data over 16 years, from a population-based cohort of Australian women moving through early adulthood (
The Australian Longitudinal Study on Women’s Health (ALSWH) is a longitudinal cohort study that examines relationships among social and lifestyle factors and women’s physical health, emotional well-being, and use of and satisfaction with health services. The entire project began with three age-group cohorts of women, who were aged 18–23 (younger cohort, born 1973–1978), 45–50 (midage cohort, born 1946–1951), and 70–75 (older cohort, born 1921–1926) when first surveyed in 1996. This article focuses on mental health trajectories in the 1973–1978 cohort, and on variables at Survey 1 (1996, aged 18–23) and at Survey 6 (2012, aged 34–39) that may be associated with these trajectories.
Women were initially selected from the Australian national health insurance database (Medicare), which includes all citizens and permanent residents. The sampling strategy was stratified random, with systematic oversampling of women from rural and remote areas. Details of the samples and recruitment methods have been described elsewhere (
Although 14,247 women were recruited to the 1973–1978 cohort, this analysis focuses on the 5,171 women in this cohort (36% of the initial sample) who responded to all of the first six surveys: Survey 1 (1996, aged 18–23); Survey 2 (2000, aged 22–27); Survey 3 (2003, aged 25–30); Survey 4 (2006, aged 28–33); Survey 5 (2009, aged 31–36); and Survey 6 (2012, aged 34–39).
Mental health was measured at each survey with the five-item Mental Health Index (MHI-5) from the SF-36 (
The following variables were measured at Survey 1 and at Survey 6 (unless indicated otherwise).
Area of residence, derived from respondents’ home address, was categorized using standard Australian classification as major cities, inner regional, outer regional, and remote/very remote (
Parent education, asked at Survey 2 only but assumed to be relatively constant, was used as a proxy for social class of origin. We categorized the reported education level of the higher-educated parent as university, trade or technical college, and school only. This variable was included in the analysis of predictors of trajectories but not as an outcome. The woman’s own education level was categorized in the same way. This variable was used as an outcome, but not as a predictor, because many of the women were still completing their education at Survey 1 (at that time, slightly under 50% were studying, including 12% who were still at secondary school).
Ability to manage on available income was used as a proxy for financial circumstances. Five response options were grouped into three categories for analysis: no difficulty, difficult some of the time, and impossible/difficult all the time. Relationship status was categorized as married; cohabiting; separated, divorced, or widowed; and never married. A work/study variable was derived from a series of questions about time use and categorized as working only, both working and studying, studying only, and neither working nor studying. Motherhood was categorized as yes or no on the basis of a question about live births.
Alcohol consumption was measured with standard questions on frequency and quantity, and respondents were categorized as low risk, nondrinker, rarely drinks, and risky/high-risk drinker (
General health was measured with the SF-36 General Health subscale (range = 0–100, higher scores indicate better self-rated health). Because this was highly skewed, we created three groups, separately for Survey 1 and at Survey 6, both based on the distribution of this variable at Survey 1 among those women included in the analysis: high (>82); moderate (>67 and ≤82); low (≤67).
Primary care physician visits in the previous 12 months were self-reported and categorized as 0, 1–2, 3–4, and 5 or more.
Psychosocial factors
Women who reported ever having been told by a doctor that they suffered from depression were categorized as yes, others as no. Women who reported ever having been in a violent relationship with a partner/spouse were categorized as yes, others as no. Weight/shape dissatisfaction was assessed using two items from the Eating Disorder Examination Questionnaire (
All analyses were performed in STATA 13.1 (Stata Corp, College Station, TX). First, mental health scores at Survey 1 were compared between those with complete data across all six surveys, who were included in these analyses, and all others, using analysis of variance, to assess any selection bias.
Mental health trajectory groups were identified using group-based trajectory modeling, a form of latent class growth modeling that identifies clusters of individuals following the same or similar trajectories (
Of the initial 14,247 women recruited to the study, 5,171 (36%) responded to all six surveys and were included in the analyses. At Survey 1, there were small but at times statistically significant differences between those included and those excluded because of subsequent missing data. Women who had missing surveys were more likely to have low mental health, be from a non-English-speaking background, experience financial difficulty, be neither working nor studying, and have children. They were also more likely to be current smokers, to report poor general health, and to have experienced intimate partner violence (see Supplementary Table S1 for a comparison of those included and those excluded on the basis of missing data).
Group-based trajectory modeling indicated four groups as the best solution, with the best model fit achieved using a polynomial order of: intercept, linear, cubic and cubic (BIC = −11,847.85, N = 5,171).
At Survey 1, when the participants were aged 18 to 23, there were several demographic differences among the trajectory groups. Those with improving mental health had initially found it very difficult to manage on available income, compared to the reference group with consistently high mental health, and at this time were also more likely to married and less likely to be studying. Those with varying mental health were also more likely than the reference group to experience some difficulty managing financially. Those with frequently low mental health were likely to speak a language other than English and report difficulty managing financially, and were likely to be neither working nor studying. There were no differences between the trajectory groups in initial area of residence, parental education, or motherhood status.
Concerning health behaviors at Survey 1, those with improving mental health were less likely to be overweight; those with varying mental health were more likely to be current smokers; and the frequently low mental health group were more likely to be underweight than the reference group. There were no differences in alcohol use or physical activity between trajectory groups.
There were several differences on physical and psychosocial variables. Those with improving mental health were initially characterized by low general health, a history of partner abuse, and high weight or shape dissatisfaction. Those with varying mental health were characterized by low general health, high rate of primary care physician visits, higher likelihood of a previous diagnosis of depression, and weight or shape dissatisfaction. Those with frequently low mental health were initially characterized by low general health, higher likelihood of a previous diagnosis of depression, a history of partner abuse, and weight or shape dissatisfaction.
Concerning health behaviors, at Survey 6 the improving mental health group were more likely to be nondrinkers or rare drinkers and to be former smokers than the reference group; they were also more likely to be underweight and less likely to be obese. The varying mental health group were more likely to drink alcohol rarely and to be former smokers; they were also more likely to be underweight and less likely to be overweight. The frequently low mental health group were characterized by greater likelihood of being in any alcohol consumption category other than low-risk drinking, and of being either current or former smokers.
The physical and emotional health variables again showed several differences. Those with improving mental health were more likely to report low general health, previous diagnosis of depression, and a history of partner abuse, than the reference group. Those with varying mental health and those with frequently low mental health were more likely to report low or moderate general health, previous diagnosis of depression, a history of partner abuse, and weight or shape dissatisfaction, than the reference group.
Longitudinal data from 5,171 women from a representative population-based study of young Australian women, initially aged 18 to 23 and followed on six occasions over 16 years, were used to identify mental health trajectory groups. We used the SF-36 Mental Health Index (MHI-5) to categorize each woman as having low or high mental health at each survey, according to previously established cut-offs. Using group-based trajectory modeling, we identified four distinct groups. Just over half the women met our criterion for high mental health at every survey. Around 10% experienced low mental health at the first or second survey but not subsequently, around a quarter showed a variable pattern over the 16 years, and around 10% experienced low mental health at most or all of the surveys.
We then used multinomial logistic regressions, first to identify variables at Survey 1 that might predict mental health trajectory over the next 16 years; and second to identify differences among the groups at Survey 6. The analysis has limitations that are typical of large-scale population-based cohort studies: a reliance on self-report, with some inconsistent reporting over time (e.g., some women changed their self-described smoking history from exsmoker to never-smoker between Surveys 1 and 6), some small demographic biases in inclusion, and biases in retention. However, the large sample size and use of well-validated measures designed for population surveys provide a degree of confidence in the pattern of findings.
A life course perspective is valuable in contextualizing the discussion of demographic, lifestyle, health-related, and psychosocial predictors and subsequent correlates of mental health patterns in early adulthood. This perspective emphasizes the cumulative importance of prior experiences as contributors to current health outcomes and health determinants, with the understanding that these factors unfold relative to one another (e.g.,
Demographically, there were few differences among the four trajectory groups at Survey 1, when the women were aged 18 to 23. Those who would go on to have frequently low mental health were notable in that they were most likely to speak a language other than English at home and to be neither working nor studying; in addition, all groups other than those who maintained high mental health reported difficulty managing on their income. The improving mental health group, who had low mental health initially but not later in the survey period, were also more likely to be married and less likely to be studying without also working.
These findings are generally consistent with other research, both from Australia (e.g.,
The finding that those with improving mental health—who generally had low mental health at Survey 1—were married might appear to contradict extensive evidence linking marriage with positive mental health (e.g.,
There were no clear patterns of health-related behaviors at baseline predicting membership of mental health trajectory groups. Alcohol consumption, smoking, body weight, and physical activity all showed no strong or consistent relationships with later mental health. This may be seen as inconsistent with studies of adolescents (e.g.,
The health and psychosocial variables at Survey 1 may be more useful in understanding future trajectories of mental health. Although all comparison groups reported poor physical health by comparison with the consistently high trajectory group, the differences between trajectory groups on the psychosocial variables were more nuanced. Those in the varying and frequently low mental health groups were more likely to report a previous diagnosis of depression, although those in the improving group were not, suggesting that we may have in fact identified a group of women whose experience with poor mental health is a single isolated incident. The improving and frequently low groups—who both had low mean mental health at Survey 1—were more likely to report partner abuse and, given the age of these women at Survey 1, that abuse is likely to be relatively recent.
Patterns of association between trajectory groups and many of the same variables at Survey 6, when the women were aged 34 to 39, were somewhat different. Overall, there were very few differences between the improving mental health group and the consistently high group, both of whom were experiencing positive mental health at Survey 6. Those with improving mental health were more likely to have smoked in the past, to have been diagnosed with depression at some stage, and to have experienced partner abuse at some stage. Currently, the only differences were that the improving group were more likely than the consistently high group to drink alcohol rarely or not at all; to be underweight and not obese; and to be in the lowest tertile of general health.
By contrast, there were differences from the reference group on most of the variables for the varying mental health and the frequently low groups at Survey 6. Demographically, both groups reported difficulty managing on their incomes, and the varying group were also more likely to be divorced, separated or widowed. The largest demographic difference was in rates of motherhood. Additional analyses (not shown) indicate that 79% of those with consistently high mental were mothers by Survey 6, when they were aged 34 to 39, and the improving mental health trajectory group were not significantly different, with 75% being mothers. Although the effect for the varying mental health group was significant, the rate of motherhood at 73% was not meaningfully different from the reference group. By contrast, only 64% of those with frequently low mental health were mothers by this survey, despite the fact that this group did not differ from the reference group in relationship status. This is concerning in the light of separate analyses from this cohort (
Evidence from the United States (
The health behavior patterns of these two groups were generally less positive than those of the consistently high mental health group, with generally more extreme relative risk ratios for the frequently low mental health group than the varying mental health group. The varying mental health group were more likely to drink alcohol rarely, to be exsmokers, and to be underweight. The frequently low mental health group were more likely to report any pattern of alcohol use except low-risk drinking; they were also more likely to be current or exsmokers. Of the psychosocial variables, both these groups were also more likely to report moderate or low general health, previous depression, a history of partner abuse, and current weight or shape concerns. These differences suggest a pervasive and generalized range of problems among the women categorized in these groups, including unhealthy lifestyles and poor general and emotional health.
This research is of particular interest for health policy and health promotion interventions because of the potential to intervene to change life-course trajectories during early adulthood (e.g.,
The differences in health behaviors should also be considered from a life course perspective, because choices and changes made in early adulthood can have lasting effects into adulthood (
All three comparison groups rated their general health as poor and reported dissatisfaction with their weight or shape at Survey 1, by comparison with those with consistently high mental health. These effects were maintained at Survey 6 by the frequently low and variable mental health groups, but the improving mental health group was no longer different from the reference group. This is consistent with the well-established link between mental and physical health (e.g.,
Overall, our findings seem consistent with the work of others (e.g.,
In summary, distinct trajectories of mental health can be identified in a population of young Australian women over a 16-year period: Women with frequently low and varying mental health are particularly at risk of other indicators of psychological distress, such as financial difficulty, and are more likely than others to remain childless. This population-level study provides a perspective that complements research focusing on individuals with clinical depression, demonstrating the potentially significant long-term outcomes among women of recurrent mental health problems across early adulthood.
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Submitted: January 8, 2015 Revised: August 26, 2015 Accepted: September 9, 2015