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- Nachgewiesen in: USPTO Patent Applications
- Sprachen: English
- Document Number: 20140141102
- Publication Date: May 22, 2014
- Appl. No: 13/880031
- Application Filed: October 27, 2011
- Assignees: DIGNITY HEALTH (Phoenix, AZ, US)
- Claim: 1. A method of extending pregnancy term in a subject in need thereof, comprising: providing a quantity of a composition comprising a 19-norprogesterone, or a pharmaceutical equivalent, derivative, analog, and/or salt thereof; and administering the quantity of the composition to the subject in need thereof.
- Claim: 2. The method of claim 1, wherein the 19-norprogesterone comprises a compound of the formula: [chemical expression included] or a pharmaceutical equivalent, derivative, analog, and/or salt thereof.
- Claim: 3. The method of claim 1, wherein the composition further comprises one or more solubilizing factors.
- Claim: 4. The method of claim 3, wherein the one or more solubilizing factors is selected from the group consisting of: cyclodextrins, sesame oil, fish oil, corn oil, olive oil, coconut oil, krill oil, omega fatty acids, mineral oil, peppermint oil, flaxseed oil, vitamin E oil, argan oil, saline solution and glucose solution.
- Claim: 5. The method of claim 1, wherein the composition is administered through nasal, oral, subcutaneous, transmucosal, transdermal, parenteral, implantable pump, continuous infusion, topical, intradermal, intravenous, intramuscular, intraperitoneal, inhalation, rectal, non-vaginal and/or vaginal delivery.
- Claim: 6. The method of claim 1, further comprising administering of one or more compounds selected from the group consisting of: nifedipine, indomethacin, magnesium sulfate, oxytocin antagonists, and tocolytics.
- Claim: 7. The method of claim 6, wherein the one or more compounds is administered after administering the quantity of the composition comprising a 19-norprogesterone, or a pharmaceutical equivalent, derivative, analog, and/or salt thereof.
- Claim: 8. The method of claim 1, wherein the composition is administered at least twice daily.
- Claim: 9. The method of claim 1, wherein the composition is administered to the subject in the range of: 0.01-0.1 mg, 0.1-0.5 mg 0.5-1 mg, 1-5 mg, 5-10 mg, 10-15 mg, 15-20 mg, and/or 20-100 mg.
- Claim: 10. The method of claim 1, wherein the pregnancy term is at least 22 weeks.
- Claim: 11. The method of claim 1, wherein the pregnancy term is at least 37 weeks.
- Claim: 12. A pharmaceutical composition, comprising a therapeutically effective amount of a 19-norprogesterone, or a pharmaceutical equivalent, derivative, analog, and/or salt thereof, and a pharmaceutically acceptable carrier.
- Claim: 13. The pharmaceutical composition of claim 12, wherein the 19-norprogesterone comprises a compound of the formula: [chemical expression included] or a pharmaceutical equivalent, derivative, analog, and/or salt thereof.
- Claim: 14. The pharmaceutical composition of claim 12, wherein the composition further comprises one or more solubilizing factors.
- Claim: 15. The pharmaceutical composition of claim 14, wherein the one or more solubilizing factors is selected from the group consisting of cyclodextrins, sesame oil, fish oil, corn oil, olive oil, coconut oil, krill oil, omega fatty acids, mineral oil, peppermint oil, flaxseed oil, vitamin E oil, argan oil, saline solution and glucose solution.
- Claim: 16. The pharmaceutical composition of claim 12, further comprising one or more compounds selected from the group consisting of: nifedipine, indomethacin, magnesium sulfate, oxytocin antagonists, and tocolytics.
- Claim: 17. The pharmaceutical composition of claim 12 provided in a dosage in the range of: 0.01-0.1 mg, 0.1-0.5 mg 0.5-1 mg, 1-5 mg, 5-10 mg, 10-15 mg, 15-20 mg, and/or 20-100 mg.
- Claim: 18. A method of treating a disease and/or condition in a subject in need thereof, comprising: providing a quantity of a composition comprising a 19-norprogesterone, or a pharmaceutical equivalent, derivative, analog, and/or salt thereof; and administering the quantity of the composition to the subject in need thereof.
- Claim: 19. The method of claim 18, wherein the 19-norprogesterone comprises a compound of the formula: [chemical expression included] or a pharmaceutical equivalent, derivative, analog, and/or salt thereof.
- Claim: 20. The method of claim 18, wherein the composition further comprises one or more solubilizing factors.
- Claim: 21. The method of claim 20, wherein the one or more solubilizing factors is selected from the group consisting of: cyclodextrins, sesame oil, fish oil, corn oil, olive oil, coconut oil, krill oil, omega fatty acids, mineral oil, peppermint oil, flaxseed oil, vitamin E oil, argan oil, saline solution and glucose solution.
- Claim: 22. The method of claim 18, wherein the composition is administered through nasal, oral, subcutaneous, transmucosal, transdermal, parenteral, implantable pump, continuous infusion, topical, intradermal, intravenous, intramuscular, intraperitoneal, inhalation, rectal, non-vaginal and/or vaginal delivery.
- Claim: 23. The method of claim 18, wherein composition further comprises administering one or more compounds selected from the group consisting of: nifedipine, indomethacin, magnesium sulfate, oxytocin antagonists, and tocolytics.
- Claim: 24. The method of claim 23, wherein the one or more compounds is administered after administering the quantity of the composition comprising a 19-norprogesterone, or a pharmaceutical equivalent, derivative, analog, and/or salt thereof.
- Claim: 25. The method of claim 18, wherein the composition is administered twice daily.
- Claim: 26. The method of claim 18, wherein the composition is administered to the subject in the range of 0.01-0.1 mg, 0.1-0.5 mg 0.5-1 mg, 1-5 mg, 5-10 mg, 10-15 mg, 15-20 mg, and/or 20-100 mg.
- Claim: 27. The method of claim 18, wherein the disease and/or condition is selected from the group consisting of: preterm labor, term labor, luteal insufficiency, dysmenorrhea, dysfunctional uterine bleeding, and combinations thereof.
- Claim: 28. The method of claim 27, wherein the disease and/or condition is dysmenorrhea.
- Claim: 29. The method of claim 27, wherein the disease and/or condition is luteal insufficiency.
- Current U.S. Class: 424/682
- Current International Class: 61; 61; 61; 61; 61; 61; 61
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