Evaluation of an alpha-cypermethrin + PBO mixture long-lasting insecticidal net VEERALIN® LN against pyrethroid resistant Anopheles gambiae s.s.: an experimental hut trial in M’bé, central Côte d’Ivoire
In: Parasites & Vectors, Jg. 12 (2019), Heft 1, S. 1-10
Online
academicJournal
Zugriff:
Abstract Background Long-lasting insecticidal nets (LLINs) are the primary method of malaria prevention. However, the widespread resistance to pyrethroids among major malaria vector species represents a significant threat to the continued efficacy of pyrethroid LLIN. Piperonyl butoxide (PBO) is a synergist that inhibits the activity of metabolic enzymes of the cytochrome P450 family known to detoxify insecticides including pyrethroids. Synergist LLIN incorporating PBO and a pyrethroid may provide improved control compared to pyrethroid-only LLIN. Methods The efficacy of VEERALIN® LN (VKA polymers Pvt Ltd, India), an alpha-cypermethrin PBO synergist net was evaluated in experimental huts in M’bé, central Côte d’Ivoire against wild pyrethroid resistant Anopheles gambiae s.s. Comparison was made with a standard alpha-cypermethrin-treated net (MAGNet® LN, VKA polymers Pvt Ltd, India). Nets were tested unwashed and after 20 standardized washes. Results VEERALIN® LN demonstrated improved efficacy compared to MAGNet® LN against wild free-flying pyrethroid-resistant An. gambiae s.s. Before washing, VEERALIN® LN produced mortality of An. gambiae s.s. (51%) significantly higher than the standard pyrethroid-only net (29%) (P
Titel: |
Evaluation of an alpha-cypermethrin + PBO mixture long-lasting insecticidal net VEERALIN® LN against pyrethroid resistant Anopheles gambiae s.s.: an experimental hut trial in M’bé, central Côte d’Ivoire
|
---|---|
Autor/in / Beteiligte Person: | Oumbouke, Welbeck A. ; Rowland, Mark ; Koffi, Alphonsine A. ; Alou, Ludovic P. A. ; Camara, Soromane ; N’Guessan, Raphael |
Link: | |
Zeitschrift: | Parasites & Vectors, Jg. 12 (2019), Heft 1, S. 1-10 |
Veröffentlichung: | BMC, 2019 |
Medientyp: | academicJournal |
ISSN: | 1756-3305 (print) |
DOI: | 10.1186/s13071-019-3796-x |
Schlagwort: |
|
Sonstiges: |
|