Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe
In: Emerging Infectious Diseases, Jg. 27 (2021), Heft 6, S. 1616-1626
Online
academicJournal
Zugriff:
In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most E30 cases affected persons 0–4 years of age (29%) and 25–34 years of age (27%). Sequences were divided into 6 genetic clades (G1–G6). Most (53%) sequences belonged to G1, followed by G6 (23%), G2 (17%), G4 (4%), G3 (0.3%), and G5 (0.2%). Each clade encompassed unique individual recombinant forms; G1 and G4 displayed >2 unique recombinant forms. Rapid turnover of new clades and recombinant forms occurred over time. Clades G1 and G6 dominated in 2018, suggesting the E30 upsurge was caused by emergence of 2 distinct clades circulating in Europe. Investigation into the mechanisms behind the rapid turnover of E30 is crucial for clarifying the epidemiology and evolution of these enterovirus infections.
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Molecular Epidemiology and Evolutionary Trajectory of Emerging Echovirus 30, Europe
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Autor/in / Beteiligte Person: | Kimberley S.M. Benschop ; Broberg, Eeva K. ; Hodcroft, Emma ; Schmitz, Dennis ; Albert, Jan ; Baicus, Anda ; Bailly, Jean-Luc ; Baldvinsdottir, Gudrun ; Berginc, Natasa ; Blomqvist, Soile ; Böttcher, Sindy ; Brytting, Mia ; Bujaki, Erika ; Cabrerizo, Maria ; Celma, Cristina ; Cinek, Ondrej ; Eric C.J. Claas ; Cremer, Jeroen ; Dean, Jonathan ; Dembinski, Jennifer L. ; Demchyshyna, Iryna ; Diedrich, Sabine ; Dudman, Susanne ; Dunning, Jake ; Dyrdak, Robert ; Emmanouil, Mary ; Farkas, Agnes ; Cillian De Gascun ; Fournier, Guillaume ; Georgieva, Irina ; Gonzalez-Sanz, Ruben ; Jolanda van Hooydonk-Elving ; Jääskeläinen, Anne J. ; Jancauskaite, Ruta ; Keeren, Kathrin ; Fischer, Thea K. ; Krokstad, Sidsel ; Nikolaeva–Glomb, Lubomira ; Novakova, Ludmila ; Midgley, Sofie E. ; Mirand, Audrey ; Molenkamp, Richard ; Morley, Ursula ; Mossong, Joël ; Muralyte, Svajune ; Murk, Jean-Luc ; Nguyen, Trung ; Nordbø, Svein A. ; Österback, Riikka ; Pas, Suzan ; Pellegrinelli, Laura ; Pogka, Vassiliki ; Prochazka, Birgit ; Rainetova, Petra ; Marc Van Ranst ; Roorda, Lieuwe ; Schuffenecker, Isabelle ; Schuurman, Rob ; Stoyanova, Asya ; Templeton, Kate ; Verweij, Jaco J. ; Voulgari-Kokota, Androniki ; Vuorinen, Tytti ; Wollants, Elke ; Wolthers, Katja C. ; Zakikhany, Katherina ; Neher, Richard ; Harvala, Heli ; Simmonds, Peter |
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Zeitschrift: | Emerging Infectious Diseases, Jg. 27 (2021), Heft 6, S. 1616-1626 |
Veröffentlichung: | Centers for Disease Control and Prevention, 2021 |
Medientyp: | academicJournal |
ISSN: | 1080-6040 (print) ; 1080-6059 (print) |
DOI: | 10.3201/eid2706.203096 |
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