Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
In: Nature Communications, Jg. 12 (2021), Heft 1, S. 1-16
Online
academicJournal
Zugriff:
Identifying the molecular mechanisms of response to systemic therapy in prostate cancer remains crucial. Here, the authors apply single cell-ATAC and RNAseq to models of early treatment response and resistance to enzalutamide and identify chromatin and gene expression patterns that can predict treatment response.
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Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
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Autor/in / Beteiligte Person: | Taavitsainen, S. ; Engedal, N. ; Cao, S. ; Handle, F. ; Erickson, A. ; Prekovic, S. ; Wetterskog, D. ; Tolonen, T. ; Vuorinen, E. M. ; Kiviaho, A. ; Nätkin, R. ; Häkkinen, T. ; Devlies, W. ; Henttinen, S. ; Kaarijärvi, R. ; Lahnalampi, M. ; Kaljunen, H. ; Nowakowska, K. ; Syvälä, H. ; Bläuer, M. ; Cremaschi, P. ; Claessens, F. ; Visakorpi, T. ; Tammela, T. L. J. ; Murtola, T. ; Granberg, K. J. ; Lamb, A. D. ; Ketola, K. ; Mills, I. G. ; Attard, G. ; Wang, W. ; Nykter, M. ; Urbanucci, A. |
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Zeitschrift: | Nature Communications, Jg. 12 (2021), Heft 1, S. 1-16 |
Veröffentlichung: | Nature Portfolio, 2021 |
Medientyp: | academicJournal |
ISSN: | 2041-1723 (print) |
DOI: | 10.1038/s41467-021-25624-1 |
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