Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia
In: Nature Communications, Jg. 11 (2020), Heft 1, S. 1-16
Online
academicJournal
Zugriff:
Dysfunction of GABAergic neurons in the prefrontal cortex has been reported in schizophrenia. Here, the authors use the apomorphine-susceptible rat, which displays some schizophrenia-like behaviors, and show that interneurons in the medial prefrontal cortex are hypomyelinated, which may contribute to this behavioral phenotype.
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Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia
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Autor/in / Beteiligte Person: | Maas, Dorien A. ; Eijsink, Vivian D. ; Spoelder, Marcia ; Josephus A. van Hulten ; Peter De Weerd ; Homberg, Judith R. ; Vallès, Astrid ; Nait-Oumesmar, Brahim ; Martens, Gerard J. M. |
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Zeitschrift: | Nature Communications, Jg. 11 (2020), Heft 1, S. 1-16 |
Veröffentlichung: | Nature Portfolio, 2020 |
Medientyp: | academicJournal |
ISSN: | 2041-1723 (print) |
DOI: | 10.1038/s41467-020-16218-4 |
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