NADPH-generating dehydrogenases: their role in the mechanism of protection against nitro-oxidative stress induced by adverse environmental conditions
In: Frontiers in Environmental Science, Jg. 2 (2014-12-01)
Online
academicJournal
Zugriff:
NADPH is an essential reductive coenzyme in biosynthetic processes such as cell growth, proliferation and detoxification in eukaryotic cells. It is required by antioxidative systems such as the ascorbate-glutathione cycle and is also necessary for the generation of superoxide radicals by plant NADPH oxidases and for the generation of nitric oxide (NO) by L-arginine-dependent nitric oxide syntase. This coenzyme is principally re-generated by a group of NADP-dehydrogenases enzymes including glucose-6-phosphate dehydrogenase (G6PDH) and 6-phosphogluconate dehydrogenase (6PGDH), both belonging to the pentose phosphate pathway, the NADP-malic enzyme (NADP-ME) and NADP-isocitrate dehydrogenase (NADP-ICDH). In this study, current perspectives on these enzymes in higher plants under different stress situations are reviewed and it is also pointed out that this group of NADPH-generating dehydrogenases is a key element in supporting the mechanism of response to nitro-oxidative stress situations.
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NADPH-generating dehydrogenases: their role in the mechanism of protection against nitro-oxidative stress induced by adverse environmental conditions
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Autor/in / Beteiligte Person: | Francisco Javier Corpas ; Juan B Barroso |
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Zeitschrift: | Frontiers in Environmental Science, Jg. 2 (2014-12-01) |
Veröffentlichung: | Frontiers Media S.A., 2014 |
Medientyp: | academicJournal |
ISSN: | 2296-665X (print) |
DOI: | 10.3389/fenvs.2014.00055 |
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