SARS-CoV-2 seroprevalence and antibodies persistence among health care workers after the first COVID-19 wave in nine hospitals in Western France
In: ISSN: 2666-9919 ; Infectious Diseases Now ; https://hal.science/hal-03789879 ; Infectious Diseases Now, 2022, 52 (8), pp.447-452. ⟨10.1016/j.idnow.2022.09.004⟩, 2022
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Zugriff:
International audience ; OBJECTIVES: To estimate the SARS-CoV-2 IgG seroprevalence rate in healthcare workers (HCWs) from Western France after the first 2020 wave, its determinants and the kinetics of total SARS-CoV-2 antibodies. PATIENTS AND METHODS: Overall, 9,453 HCWs responded to a self-questionnaire and underwent a lateral flow immunoassay to assess SARS-CoV-2 IgG presence. For 72 HCWs who tested positive, total anti-nucleocapsid antibodies were assessed at day 0, 30, and 90. RESULTS: SARS-CoV-2 IgG seroprevalence rate was 1.06% [0.86%-1.27%]. Factors associated with IgG presence were gender, performing upper respiratory tract samples, contact with HCWs or household members diagnosed with COVID-19. Total antibodies decreased between day 0 and day 90, with anosmia or ageusia, and were higher in HCWs older than 50 years. CONCLUSION: We reported a low prevalence rate of IgG and identified several risk factors associated with its presence and persistence of total antibodies. Additional studies are needed to confirm these observations.
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SARS-CoV-2 seroprevalence and antibodies persistence among health care workers after the first COVID-19 wave in nine hospitals in Western France
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| Autor/in / Beteiligte Person: | Garlantezec, R ; Tadié, E ; Heslan, C ; Gary-Bobo, P ; Oumari, S ; Saade, A ; Sitruk, A ; Tattevin, P ; Thibault, V. ; Paris, C ; Institut de recherche en santé, environnement et travail (Irset) ; Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) ; Centre Hospitalier Universitaire de Rennes CHU Rennes = Rennes University Hospital Ponchaillou ; ARN régulateurs bactériens et médecine (BRM) ; Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) ; This study was funded by a grant from the Nominoe Fund and the Rennes CHU. |
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| Zeitschrift: | ISSN: 2666-9919 ; Infectious Diseases Now ; https://hal.science/hal-03789879 ; Infectious Diseases Now, 2022, 52 (8), pp.447-452. ⟨10.1016/j.idnow.2022.09.004⟩, 2022 |
| Veröffentlichung: | HAL CCSD ; Elsevier, 2022 |
| Medientyp: | academicJournal |
| DOI: | 10.1016/j.idnow.2022.09.004 |
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