Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya
In: Transactions of the Royal Society of Tropical Medicine and Hygiene ; 97 ; 5 ; 513-4, 2022
Online
academicJournal
Zugriff:
Sickle cell genotype prevalence was 26% in a malaria-holoendemic lowland area compared with 3% in a highland area of Kenya. The prevalence of glucose-6-phosphate dehydrogenase deficiency was 7% and 1% in holoendemic lowland and highland areas, respectively. Lack of protective polymorphisms may contribute to morbidity and mortality during outbreaks of malaria in the highlands.
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Frequencies of sickle cell trait and glucose-6-phosphate dehydrogenase deficiency differ in highland and nearby lowland malaria-endemic areas of Kenya
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Autor/in / Beteiligte Person: | Moormann, Ann M. ; Embury, Paula E. ; Opondo, J. ; Sumba, Peter Odada ; Ouma, J. H. ; Kazura, James W. ; John, Chandy C. ; Department of Pediatrics ; Department of Quantitative Health Sciences |
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Zeitschrift: | Transactions of the Royal Society of Tropical Medicine and Hygiene ; 97 ; 5 ; 513-4, 2022 |
Veröffentlichung: | 2022 |
Medientyp: | academicJournal |
DOI: | 10.1016/S0035-9203(03)80010-X |
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