Serological evidence of West Nile virus infection in human populations and domestic birds in the Northwest of Morocco
In: ISSN: 0147-9571 ; Comparative Immunology, Microbiology and Infectious Diseases ; https://pasteur.hal.science/pasteur-03323236 ; Comparative Immunology, 2021
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Zugriff:
International audience ; West Nile virus (WNV) was recently detected in Culex pipiens mosquitoes in Morocco. The aim of this study was to evaluate the seroprevalence of WNV in humans and in domestic birds in two regions of Morocco by the detection of IgG antibodies. Blood samples were obtained from 91 human patients and 92 domestic birds from September to December 2019. All study samples were tested using competitive enzyme-linked immunosorbent assay (cELISA) and WNV neutralization tests (VNT) were performed on positive sera. Of all samples, 4 (4.39 %) humans and 4 (4.34 %) birds were found to be seropositive for flaviviruses by the cELISA test. The VNT revealed that three of the four human samples detected positive by cELISA contained neutralizing antibodies against WNV. Two bird samples were confirmed positive by VNT. These results show a significant seroprevalence of anti-WNV antibodies and therefore suggest the active circulation and exposure of human and bird populations in the northwest of Morocco.
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Serological evidence of West Nile virus infection in human populations and domestic birds in the Northwest of Morocco
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| Autor/in / Beteiligte Person: | Assaid, Najlaa ; Arich, Soukaina ; Ezzikouri, Sayeh ; Benjelloun, Soumaya ; Dia, Moussa ; Faye, Oumar ; Akarid, Khadija ; Beck, Cécile ; Lecollinet, Sylvie ; Failloux, Anna-Bella ; Sarih, M’hammed ; Laboratoire de Parasitologie et Maladies Vectorielles Maroc ; Institut Pasteur du Maroc ; Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP) ; Université Hassan II Casablanca (UH2MC) ; Laboratoire des Hépatites Virales Casablanca, Maroc (LHV) ; Département de virologie - Virology Department Dakar ; Institut Pasteur de Dakar ; Virologie UMR1161 (VIRO) ; École nationale vétérinaire - Alfort (ENVA)-Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE) ; Arbovirus et Insectes Vecteurs - Arboviruses and Insect Vectors ; Institut Pasteur Paris (IP) ; This study was funded by Institut Pasteur of Morocco. |
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| Zeitschrift: | ISSN: 0147-9571 ; Comparative Immunology, Microbiology and Infectious Diseases ; https://pasteur.hal.science/pasteur-03323236 ; Comparative Immunology, 2021 |
| Veröffentlichung: | HAL CCSD ; Elsevier, 2021 |
| Medientyp: | academicJournal |
| DOI: | 10.1016/j.cimid.2021.101646 |
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