Administration of TBK1 inhibitor (TBK1/IKKε-IN-2) on mice survival at different time points.
2023
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Zugriff:
3-day-old BALB/c mice were inoculated i.p. with 2.86 × 10 6 TCID 50 EV-A71, followed by i.p. injection with TBK1 inhibitor (dissolved in DMSO) to achieve a dose of 2.5 μg per mouse at different time points (1, 6, 12, 24, 48, 72 hpi). Survival rates of infected and control mice were record until 15 dpi. Statistical differences of survival rates between control and treated mice were assessed with the Mantel-Cox log rank test and survival curves were plotted using the Kaplan-Meier method. n = 10 per group; * P < 0.05; ** P < 0.01. (TIF)
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Administration of TBK1 inhibitor (TBK1/IKKε-IN-2) on mice survival at different time points.
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Autor/in / Beteiligte Person: | Wangquan Ji (10887180) ; Tiantian Sun (154175) ; Dong Li (212687) ; Shuaiyin Chen (3816457) ; Haiyan Yang (659313) ; Yuefei Jin (4722396) ; Guangcai Duan (517687) |
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Veröffentlichung: | 2023 |
Medientyp: | Bild |
DOI: | 10.1371/journal.pntd.0011001.s004 |
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