Heterogeneity in the Prevalence of High-Risk Human Papillomavirus Infection in Human Immunodeficiency Virus-Negative and Human Immunodeficiency Virus-Positive Men Who Have Sex With Men in West Africa
In: Clinical Infectious Diseases, Jg. 73 (2021), Heft 12, S. 2184-2192
Online
academicJournal
Zugriff:
Background Men who have sex with men (MSM) are at high risk of human papillomavirus (HPV) infection. We assessed (i) the prevalence of high-risk HPV (HR-HPV) infection and associated factors, and (ii) the prevalence of vaccine-preventable HPV infections in MSM in Burkina Faso, Côte d’Ivoire, Mali, and Togo. Methods A cross-sectional study was conducted in 2017–2018 among MSM ≥18 years old followed in community-based clinics. HPV infection was investigated in oral and anal samples using the e-BRID system. Factors associated with HR-HPV infection were identified using multivariate logistic regressions. Results Among 631 participants, 425 were HIV-negative and 206 HIV-positive. HR-HPV prevalence ranged from 9.2% to 34.8% in the former, and 33.3% to 71.0% in the latter, according to the study country. In multivariate analysis, HIV infection (adjusted odds ratio (aOR) 3.61, 95% confidence interval (CI) 2.48–5.27) and study country (4.73, 2.66–8.43 for Mali; 3.12, 1.68–5.80 for Burkina Faso; 3.51, 1.92–6.42 for Togo) were associated with HR-HPV infection. Other associated factors were low educational level, self-defined homosexual identity, and condomless anal sex. The prevalence of infections which can be prevented with bivalent, quadrivalent, and nonavalent vaccines was 5.9, 27.1, and 34.6% in HIV-negative participants, and 18.9, 43.7, and 54.9% in HIV-positive participants, respectively. Conclusions HR-HPV prevalence was very heterogeneous between the study countries in both HIV-negative and HIV-positive MSM. Vaccine-preventable HPV infections predominated. Vaccination should be proposed to young MSM to reduce the burden of HPV infection in this vulnerable population and their female partners in West Africa.
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Heterogeneity in the Prevalence of High-Risk Human Papillomavirus Infection in Human Immunodeficiency Virus-Negative and Human Immunodeficiency Virus-Positive Men Who Have Sex With Men in West Africa
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Autor/in / Beteiligte Person: | Yaya, Issifou ; Boyer, Véronique ; Ehlan, Phyllis Amivi ; Coulibaly, Alou ; Agboyibor, Mawuényégan Kouamivi ; Traoré, Issa ; Kouamé, Malan Jean-Baptiste ; Maiga, Alassane Kader ; Kotchi, Ochoh Rachelle ; Nyasenu, Yawo Tufa ; Maradan, Gwenaëlle ; Rojas-Castro, Daniela ; Diallo, Fodié ; Anoma, Camille ; Dah, Ter Tiero Elias ; Mensah, Ephrem ; Dembélé Keita, Bintou ; Spire, Bruno ; Dagnra, Claver Anoumou ; Laurent, Christian ; Ouedraogo, Sayouba ; Granouillac, Bruno ; Le Guicher, Gwenvael ; Serrano, Laetitia ; Peeters, Martine ; Couderc, Clotilde ; Sagaon-Teyssier, Luis ; Mora, Marion ; Bourrelly, Michel ; Mimi, Mohamed ; Berenger, Cyril ; Boyer, Sylvie ; Castro, Daniela Rojas ; Riegel, Lucas ; Palvadeau, Paméla ; Keita, Bintou Dembélé ; Maïga, Alassane Kader ; Camara, Drissa ; Diarra, Mahamadou ; Ouologuem, Aly ; Sangaré, Naboh ; Keita, Abdoul Aziz ; Cissé, Oumar ; Traoré, Fodé ; ANRS ; Sidaction |
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Zeitschrift: | Clinical Infectious Diseases, Jg. 73 (2021), Heft 12, S. 2184-2192 |
Veröffentlichung: | Oxford University Press (OUP), 2021 |
Medientyp: | academicJournal |
ISSN: | 1058-4838 |
DOI: | 10.1093/cid/ciab157 |
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