Chemical profiling by UHPLC-Q-TOF-HRESI-MS/MS and antibacterial properties of Entada abyssinica (Fabaceae) constituents ...
Taylor & Francis, 2023
academicJournal
Zugriff:
A rapid untargeted UHPLC-Q-TOF-ESI-MS/MS-Based metabolomic profiling of the medicinal plant Entada abyssinica was performed. A total of 18 metabolites were detected, of which 10 could not be identified. Based on this result, an extensive chemical investigation of the CH 2 Cl 2 -MeOH (1:1) extract of this plant was carried out, leading to the isolation of a new ceramide, named entadamide ( 1 ), together with nine known compounds: monomethyl kolavate ( 2 ), 24-hydroxytormentic acid ( 3 ) chondrillasterol ( 4 ), 3- O - β -D glucopyranosylstigmasterol ( 5 ), 3- O - β -D glucopyranosylsitosterol ( 6 ), quercetin 3′-methylether ( 7 ), 2,3-dihydroxypropyl icosanoate ( 8 ), 2,3-dihydroxypropyl 23-hydroxytricosanoate ( 9 ) and 2,3-dihydroxypropyl 24-hydroxytetracosanoate ( 10 ). Their structures were elucidated by the analyses of their spectroscopic and spectrometric data (1D and 2D NMR, and HRESI-MS) in comparison with those reported in the literature. Furthermore, the crude extract and some isolated compounds ...
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Chemical profiling by UHPLC-Q-TOF-HRESI-MS/MS and antibacterial properties of Entada abyssinica (Fabaceae) constituents ...
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Autor/in / Beteiligte Person: | Magnibou, Larissa M. ; Wouamba, Steven C. N. ; Yaya, Abel J. G. ; Mbougnia, Judith F. ; Njateng, Guy S. S. ; Fotso, Ghislain W. ; Henoumont, Celine ; Laurent, Sophie ; Emmanuel, Talla |
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Veröffentlichung: | Taylor & Francis, 2023 |
Medientyp: | academicJournal |
DOI: | 10.6084/m9.figshare.24585685.v1 |
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