Outcomes and Their State-level Variation in Patients Undergoing Surgery With Perioperative SARS-CoV-2 Infection in the USA. A Prospective Multicenter Study
In: ANNALS OF SURGERY, 2022, Heft 2, S. 247-251
Online
academicJournal
Zugriff:
Objective: To report the 30-day outcomes of patients with perioperative SARS-CoV-2 infection undergoing surgery in the USA. Background: Uncertainty regarding the postoperative risks of patients with SARS-CoV-2 exists. Methods: As part of the COVIDSurg multicenter study, all patients aged ≥17 years undergoing surgery between January 1 and June 30, 2020 with perioperative SARS-CoV-2 infection in 70 hospitals across 27 states were included. The primary outcomes were 30-day mortality and pulmonary complications. Multivariable analyses (adjusting for demographics, comorbidities, and procedure characteristics) were performed to identify predictors of mortality. Results: A total of 1581 patients were included; more than half of them were males (n = 822, 52.0%) and older than 50 years (n = 835, 52.8%). Most procedures (n = 1261, 79.8%) were emergent, and laparotomies (n = 538, 34.1%). The mortality and pulmonary complication rates were 11.0 and 39.5%, respectively. Independent predictors of mortality included age ≥70 years (odds ratio 2.46, 95% confidence interval [1.65-3.69]), male sex (2.26 [1.53-3.35]), ASA grades 3-5 (3.08 [1.60-5.95]), emergent surgery (2.44 [1.31-4.54]), malignancy (2.97 [1.58-5.57]), respiratory comorbidities (2.08 [1.30-3.32]), and higher Revised Cardiac Risk Index (1.20 [1.02-1.41]). While statewide elective cancelation orders were not associated with a lower mortality, a sub-analysis showed it to be associated with lower mortality in those who underwent elective surgery (0.14 [0.03-0.61]). Conclusions: Patients with perioperative SARS-CoV-2 infection have a significantly high risk for postoperative complications, especially elderly males. Postponing elective surgery and adopting non-operative management, when reasonable, should be considered in the USA during the pandemic peaks.
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Outcomes and Their State-level Variation in Patients Undergoing Surgery With Perioperative SARS-CoV-2 Infection in the USA. A Prospective Multicenter Study
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| Autor/in / Beteiligte Person: | Alser, Osaid ; Ander Dorken Gallastegi ; Gebran, Anthony ; Breen, Kerry ; Mohamad El Moheb ; Gaitanidis, Apostolos ; Naar, Leon ; Bankhead-Kendall, Brittany ; Mashbari, Hassan ; Robert D Sinyard ; Lydia R Maurer ; Paranjape, Charu ; George C Velmahos ; Nepogodiev, Dmitri ; Bhangu, Aneel ; Haytham M A Kaafarani ; Siaw-Acheampong, Kwabena ; Argus, Leah ; Chaudhry, Daoud ; Brett E Dawson ; James C Glasbey ; Rohan R Gujjuri ; Conor S Jones ; Sivesh K Kamarajah ; Khatri, Chetan ; James M Keatley ; Lawday, Samuel ; Li, Elizabeth ; Mann, Harvinder ; Ella J Marson ; Kenneth A Mclean ; Picciochi, Maria ; Elliott H Taylor ; Tiwari, Abhinav ; Joana F F Simoes ; Isobel M Trout ; Mary L Venn ; Richard J W Wilkin ; Dajti, Irida ; Gjata, Arben ; Kacimi, Oussama ; Boccalatte, Luis ; Maria Marta Modolo ; Cox, Daniel ; Pockney, Peter ; Townend, Philip ; Aigner, Felix ; Kronberger, Irmgard ; Elgun, Ahmed ; Alderazi, Amer ; Hossain, Kamral ; Padmore, Greg ; VanRamshorst, Gabrielle ; Lawani, Ismail ; Wedderburn, Duane ; Dargay, Sonam ; Feraudy, Israël ; Anis, Cerovac ; Delibegovic, Samir ; Alemayehu Ginbo Bedada ; Ataide, Gustavo ; Baiocchi, Glauco ; Buarque, Igor ; Gohar, Muhammad ; Slavchev, Mihail ; Jean Marie Vianney Butoyi ; Nwegbu, Chukwuemeka ; Agarwal, Arnav ; Brar, Amanpreet ; Martin, Janet ; Olivos, Maricarmen ; Ren, Dong-Lin ; Lou, Wenhui ; Calvache, Jose ; Carlos Jose Perez Rivera ; Ana Danic Hadzibegovic ; Kopjar, Tomislav ; Mihanovic, Jakov ; Avilés, Pablo ; Gouvas, Nikolaos ; Klat, Jaroslav ; Novysedlak, René ; Amisi, Nicolas ; Christensen, Peter ; El-Hussuna, Alaa ; Batista, Sylvia ; Lincango, Eddy ; Sameh H Emile ; Danilo Alfonso Arévalo Sandoval ; Mengistu Gebreyohanes Mengesha ; Hailu, Samuel ; Tamiru, Hailu ; Kauppila, Joonas ; Laukkarinen, Johanna ; Arnaud, Alexis ; Roumanatou Bankole Sapin ; Marenah, Kebba ; Demetrashvili, Zaza ; Andreas A Schnitzbauer ; Gruendl, Magdalena ; Albertsmeiers, Markus ; Lederhuber, Hans ; Loffler, Markus ; Bernard Ofori Appiah ; Acquah, Daniel ; Tabiri, Stephen ; Metallidis, Symeon ; Tsoulfas, Georgios ; Maria Aguilera Lorena ; Grecinos, Gustavo ; Mersich, Tamas ; Wettstein, Daniel ; Suroy, Atul ; Ghosh, Dhruv ; Pawar, Pranay ; Kembuan, Gabriele ; Brouk, Peiman ; Khosravi, Mohammad ; Mozafari, Masoud ; Adil, Ahmed ; Helen M Mohan ; Zmora, Oded ; Fiore, Marco ; Gallo, G ; Pata, Francesco ; Pellino, Gianluca ; Kuroda, Naoto ; Satoi, Sohei ; Fujimoto, Yuki ; Ayasra, Faris ; Chaar, Mohammad ; Ildar R Fakhradiyev ; Hisham, Intisar ; Jang, Jin-Young ; Fekaj, Enver ; Jamal, Mohammad ; Beisembaev, Anvar ; Elhadi, Muhammed ; Gulla, Aiste ; Samison, Luc ; Neny, Jupsi ; Chisala, Palesa ; Roslani, April ; Iran Irani Duran Sanchez ; Laura Martinez Perez Maldonado ; Antonio Ramos De La Medina ; Nunez, Jade ; Outani, Oumaima ; Nashidengo, Abd'Rashid ; Ashish Lal Shrestha ; Shah, Rakesh ; Jonker, Pascal ; Kruijff, Schelto ; Noltes, Milou ; Steinkamp, Pieter ; Willemijn van der Plas ; Varghese, Chris ; Wright, Deborah ; Neira, Jorge ; Ademuyiwa, Adesoji ; Osinaike, Babatunde ; Seyi-Olajide, Justina ; Williams, Emmanuel ; Pejkova, Sofija ; Knut Magne Augestad ; Soreide, Kjetil ; Zainab Al Balushi ; Qureshi, Ahmad ; Sayyed, Raza ; Mustafa Abu Mohsen Daraghmeh ; Abukhalaf, Sadi ; Cukier, Moises ; Munguas, Chris ; Gomez, Hugo ; Shu, Sebastian ; Vasquez, Ximena ; Marie Dione Parreno-Sacdalan ; Major, Piotr ; Azevedo, José ; Cunha, Miguel ; Santos, Irene ; Zarour, Ahmad ; Bonci, Eduard-Alexandru ; Negoi, Ionut ; Efetov, Sergey ; Litvin, Andrey ; Ntirenganya, Faustin ; AlAmeer, Ehab ; Ndong, Abdourahmane ; Radenkovic, Dejan ; Sesay, Ibrahim ; Frederick Koh Hong Xiang ; Chew Min Hoe ; James Ngu Chi Yong ; Panyko, Arpad ; Kosir, Jurij ; Bele, Uros ; Ali, Hassan ; Moore, Rachel ; Nhlabathi, Ncamsile ; Ruth Blanco Colino ; Ana Minaya Bravo ; Jayarajah, Umesh ; Wickramasinghe, Dakshitha ; Elmujtaba, Mohammed ; Jebril, William ; Rutegård, Martin ; Sund, Malin ; Gialamas, Eleftherios ; Horisberger, Karoline ; Adamina, Michel ; Alshaar, Muhammad ; 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Aneel, Bhangu ; Haytham M, A Kaafarani ; Kwabena, Siaw-Acheampong ; Leah, Argu ; Daoud, Chaudhry ; Brett, E Dawson ; James, C Glasbey ; Rohan, R Gujjuri ; Conor, S Jone ; Sivesh, K Kamarajah ; Chetan, Khatri ; James, M Keatley ; Samuel, Lawday ; Elizabeth, Li ; Harvinder, Mann ; Ella, J Marson ; Kenneth, A Mclean ; Maria, Picciochi ; Elliott, H Taylor ; Abhinav, Tiwari ; Joana F, F Simoe ; Isobel, M Trout ; Mary, L Venn ; Richard J, W Wilkin ; Irida, Dajti ; Arben, Gjata ; Oussama, Kacimi ; Luis, Boccalatte ; Daniel, Cox ; Peter, Pockney ; Philip, Townend ; Felix, Aigner ; Irmgard, Kronberger ; Ahmed, Elgun ; Amer, Alderazi ; Kamral, Hossain ; Greg, Padmore ; Gabrielle, Vanramshorst ; Ismail, Lawani ; Duane, Wedderburn ; Sonam, Dargay ; Israël, Feraudy ; Cerovac, Ani ; Samir, Delibegovic ; Gustavo, Ataide ; Glauco, Baiocchi ; Igor, Buarque ; Muhammad, Gohar ; Mihail, Slavchev ; Chukwuemeka, Nwegbu ; Arnav, Agarwal ; Amanpreet, Brar ; Janet, Martin ; Maricarmen, Olivo ; Dong-Lin, Ren ; Wenhui, Lou ; Jose, Calvache ; Tomislav, Kopjar ; Jakov, Mihanovic ; Pablo, Avilé ; Nikolaos, Gouva ; Jaroslav, Klat ; René, Novysedlak ; Nicolas, Amisi ; Peter, Christensen ; Alaa, El-Hussuna ; Sylvia, Batista ; Eddy, Lincango ; Sameh, H Emile ; Samuel, Hailu ; Hailu, Tamiru ; Joonas, Kauppila ; Johanna, Laukkarinen ; Alexis, Arnaud ; Kebba, Marenah |
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| Zeitschrift: | ANNALS OF SURGERY, 2022, Heft 2, S. 247-251 |
| Veröffentlichung: | Wolters Kluwer Health, 2022 |
| Medientyp: | academicJournal |
| DOI: | 10.1097/SLA.0000000000005310 |
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