DIAGNOSTIC CHALLENGES OF AUTOIMMUNE ENCEPHALITIS, REGARDING A CLINICAL CASE
In: Open Research Library, 2017
Online
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Zugriff:
Autoimmune encephalitis are a group of recent discovered entities, with NMDA encephalitis being the most common and well-known in the medical community. The aim of this work is to describe this neuropshychiatric condition, where 80% of patients are initially admitted to a psychiatry ward and whose prognosis depends of early institution of immunosuppressive treatment. Results and Conclusions:This case regards a 28 year-old-woman with no psychiatric background or history of drug abuse. She didnu2019t experienced any physical or psychological change until two weeks before admission to our hospital. After a significant life-event, she began to show significant humour and behaviour alterations, accompanied by loss in autobiographical memory. The blood analysis, head CT scan and EEG didnu2019t show any alterations. After admission to the psychiatry ward, despite all treatment measures, she failed to show any improvement. Three weeks after admission, she presented an worsening of clinical picture, showing decreased state of consciousness, verbal perseveration and visual hallucinations. MRI suggested limbic encephalitis. Lumbar puncture was positive for VGKC (voltage gated potassium channel) antibodies yet having no specific antigenic target. She initiated treatment with intravenous immunoglobulin and methylprednisolone, and gradually got better, although not having reached full remission.Our patient presents with a type that is very rare (anti-VGK with no specific antigen). This case is particularly important for spreading awareness in the psychiatry community about this condition.
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DIAGNOSTIC CHALLENGES OF AUTOIMMUNE ENCEPHALITIS, REGARDING A CLINICAL CASE
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Autor/in / Beteiligte Person: | Viegas, Filipa |
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Zeitschrift: | Open Research Library, 2017 |
Veröffentlichung: | Morressier, 2017 |
Medientyp: | unknown |
DOI: | 10.26226/morressier.5d1a037357558b317a140341 |
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