Similarity between UGA14 plasmid pSLT-BT-UGA14 and reference S . Typhimurium plasmids pSBLT (ST313) and pSLT-BT (D23580).
2021
academicJournal
Zugriff:
The AMR gene island is circled by dashed line, and the direct repeats in pSBLT are highlighted as yellow. There is a 19 kb inversion occurring in pSLT-BT but not in pSLT-BT-UGA14 (35838–54324 bps). There are two pSBLT genes, IS5075 and repA , that are not present in pSLT-BT-UGA14 at the 5’ and 3’ end of inversion boundaries, respectively. Although this hexameric replicative helicase RepA is missing in the UGA14 genome, IncFII family repA is present in pSLT-BT-UGA14, pSBLT and pSLT-BT. Notably, this 19 kb inversion region is overlapped with prophage regions from 52719–73452 and flanked by IS elements from 3 different backgrounds (pSBLT, pSLT-BT, and pSLT-BT-UGA14), indicating a potential recombination hotspot at this locus. (PDF)
Titel: |
Similarity between UGA14 plasmid pSLT-BT-UGA14 and reference S . Typhimurium plasmids pSBLT (ST313) and pSLT-BT (D23580).
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Autor/in / Beteiligte Person: | Jessica Z. Kubicek-Sutherland (5395283) ; Gary Xie (866) ; Migun Shakya (471213) ; Priya K. Dighe (10063316) ; Lindsey L. Jacobs (10063319) ; Hajnalka Daligault (226568) ; Karen Davenport (123069) ; Loreen R. Stromberg (3167811) ; Zachary R. Stromberg (4221139) ; Qiuying Cheng (300696) ; Prakasha Kempaiah (336992) ; John Michael Ong’echa (3608081) ; Vincent Otieno (10063322) ; Evans Raballah (3937781) ; Samuel Anyona (3938639) ; Collins Ouma (591083) ; Patrick S. G. Chain (7428695) ; Douglas J. Perkins (6831164) ; Harshini Mukundan (298919) ; Benjamin H. McMahon (8114936) ; Norman A. Doggett (10063325) |
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Veröffentlichung: | 2021 |
Medientyp: | academicJournal |
DOI: | 10.1371/journal.pntd.0008991.s005 |
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