Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali
In: ISSN: 2414-6366 ; Tropical Medicine and Infectious Disease ; https://www.hal.inserm.fr/inserm-03832308 ; Tropical Medicine and Infectious Disease, 2021, 2021
Online
academicJournal
Zugriff:
International audience ; In Mali, since 2007, artemether-lumefantrine has been the first choice against uncomplicated malaria. Despite its effectiveness, a rapid selection of markers of resistance to partner drugs has been documented. This work evaluated the treatment according to the World Health Organization's standard 28-day treatment method. The primary endpoint was the clinical and parasitological response corrected by a polymerase chain reaction. It was more than 99.9 percent, the proportion of patients with anemia significantly decrease compared to baseline (p < 0.001), and no serious events were recorded. Plasmodium falciparum remains sensitive to artemether-lumefantrine in Mali.
| Titel: |
Monitoring of the Sensitivity In Vivo of Plasmodium falciparum to Artemether-Lumefantrine in Mali
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| Autor/in / Beteiligte Person: | Diarra, Modibo ; Coulibaly, Drissa ; Tapily, Amadou ; Guindo, Boureima ; Sanogo, Koualy ; Koné, Diakalia ; Koné, Youssouf ; Koné, Karim ; Bathily, Aboudramane ; Yattara, Oumar ; Thera, Mahamadou ; Dicko, Alassane ; Djimdé, Abdoulaye ; Sagara, Issaka ; Université des Sciences, des Techniques et des Technologies de Bamako (USTTB) ; National Malaria Control Program Bamako, Mali ; Populations Services International-Mali Bamako, Mali (PSI-Mali) |
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| Zeitschrift: | ISSN: 2414-6366 ; Tropical Medicine and Infectious Disease ; https://www.hal.inserm.fr/inserm-03832308 ; Tropical Medicine and Infectious Disease, 2021, 2021 |
| Veröffentlichung: | HAL CCSD ; MDPI, 2021 |
| Medientyp: | academicJournal |
| DOI: | 10.3390/tropicalmed6010013 |
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