Bringing sensation to prosthetic hands—chronic assessment of implanted thin-film electrodes in humans
In: ISSN: 2397-4621 ; npj Flexible eletronics ; https://inria.hal.science/hal-04296540 ; npj Flexible eletronics, 2023, 2023
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Zugriff:
International audience ; Abstract Direct stimulation of peripheral nerves with implantable electrodes successfully provided sensory feedback to amputees while using hand prostheses. Longevity of the electrodes is key to success, which we have improved for the polyimide-based transverse intrafascicular multichannel electrode (TIME). The TIMEs were implanted in the median and ulnar nerves of three trans-radial amputees for up to six months. We present a comprehensive assessment of the electrical properties of the thin-film metallization as well as material status post explantationem . The TIMEs stayed within the electrochemical safe limits while enabling consistent and precise amplitude modulation. This lead to a reliable performance in terms of eliciting sensation. No signs of corrosion or morphological change to the thin-film metallization of the probes was observed by means of electrochemical and optical analysis. The presented longevity demonstrates that thin-film electrodes are applicable in permanent implant systems.
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Bringing sensation to prosthetic hands—chronic assessment of implanted thin-film electrodes in humans
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Autor/in / Beteiligte Person: | Čvančara, Paul ; Valle, Giacomo ; Müller, Matthias ; Bartels, Inga ; Guiho, Thomas ; Hiairrassary, Arthur ; Petrini, Francesco ; Raspopovic, Stanisa ; Strauss, Ivo ; Granata, Giuseppe ; Fernandez, Eduardo ; Rossini, Paolo, M ; Barbaro, Massimo ; Yoshida, Ken ; Jensen, Winnie ; Divoux, Jean-Louis ; Guiraud, David ; Micera, Silvestro ; Stieglitz, Thomas ; Department of Microsystems Engineering Freiburg (IMTEK) ; University of Freiburg Freiburg ; Ecole Polytechnique Fédérale de Lausanne (EPFL) ; The BioRobotics Institute ; Scuola Universitaria Superiore Sant'Anna Pisa (SSSUP) ; Contrôle Artificiel de Mouvements et de Neuroprothèses Intuitives (CAMIN) ; Inria Sophia Antipolis - Méditerranée (CRISAM) ; Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria) ; Università cattolica del Sacro Cuore = Catholic University of the Sacred Heart Roma (Unicatt) ; Fondazione Policlinico Universitario Agostino Gemelli, IRCCS ; Department of Electrical and Electronic Engineering University of Cagliari (DIEE) ; University of Cagliari ; Indiana University - Purdue University Indianapolis (IUPUI) ; Indiana University System ; Aalborg University Denmark (AAU) ; MXM-AXONIC ; (CMCS-EPFL), CMCS-EPFL ; European Project: 602547,EC:FP7:HEALTH,FP7-HEALTH-2013-INNOVATION-1,EPIONE(2013) ; European Project: 611687,EC:FP7:ICT,FP7-ICT-2013-10,NEBIAS(2013) |
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Zeitschrift: | ISSN: 2397-4621 ; npj Flexible eletronics ; https://inria.hal.science/hal-04296540 ; npj Flexible eletronics, 2023, 2023 |
Veröffentlichung: | HAL CCSD ; Nature partners jounal, 2023 |
Medientyp: | academicJournal |
DOI: | 10.1038/s41528-023-00284-x |
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