Hypokalemia, Cardiac Failure, and Reporting NXY-059 Safety for Acute Stroke.
In: Journal of Cardiovascular Pharmacology & Therapeutics, Jg. 11 (2006-12-01), Heft 4, S. 229-231
Online
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Zugriff:
The article discusses the efficacy of NXY-059, an alpha-phenyl-N-tert-butyl nitrone derivative, in treating acute stroke based on the results of two clinical trials. Hemorrhagic transformation occurred in patient subjects treated with NXY-059 compared to those who received placebo. The cardiac safety profile of NXY-059 should be addressed further with the higher incidence of hypokalemia in the NXY-059 group. The trials' results represent the real challenges for the further clinical development of NXY-059.
Titel: |
Hypokalemia, Cardiac Failure, and Reporting NXY-059 Safety for Acute Stroke.
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Autor/in / Beteiligte Person: | Serebruany, Victor L. |
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Zeitschrift: | Journal of Cardiovascular Pharmacology & Therapeutics, Jg. 11 (2006-12-01), Heft 4, S. 229-231 |
Veröffentlichung: | 2006 |
Medientyp: | academicJournal |
ISSN: | 1074-2484 (print) |
DOI: | 10.1177/1074248406297311 |
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