Evaluation of ten (10) SARS-CoV-2 rapid serological tests in comparison with WANTAI SARS-CoV-2 ab ELISA in Burkina Faso, West Africa.
In: Virology Journal, Jg. 20 (2023-03-30), Heft 1, S. 1-9
Online
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Zugriff:
Background: The aim of this study was to evaluate the performance of ten (10) SARS-CoV-2 serological rapid diagnostic tests in comparison with the WANTAI SARS-CoV-2 Ab ELISA test in a laboratory setting. Materials and methods: Ten (10) SARS-CoV-2 serological rapid diagnostic tests (RDTs) for SARS-CoV-2 IgG/IgM were evaluated with two (2) groups of plasma tested positive for one and negative for the other with the WANTAI SARS-CoV-2 Ab ELISA. The diagnostic performance of the SARS-CoV-2 serological RDTs and their agreement with the reference test were calculated with their 95% confidence intervals. Results: The sensitivity of serological RDTs ranged from 27.39 to 61.67% and the specificity from 93.33 to 100% compared to WANTAI SARS-CoV-2 Ab ELISA test. Of all the tests, two tests (STANDARD Q COVID-19 IgM/IgG Combo SD BIOSENSOR and COVID-19 IgG/IgM Rapid Test (Zhejiang Orient Gene Biotech Co., Ltd)) had a sensitivity greater than 50%. In addition, all ten tests had specificity greater than or equal to 93.33% each. The concordance between RDTs and WANTAI SARS-CoV-2 Ab ELISA test ranged from 0.25 to 0.61. Conclusion: The SARS-CoV-2 serological RDTs evaluated show low and variable sensitivities compared to the WANTAI SARS-CoV-2 Ab ELISA test, with however a good specificity. These finding may have implications for the interpretation and comparison of COVID-19 seroprevalence studies depending on the type of test used. [ABSTRACT FROM AUTHOR]
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Evaluation of ten (10) SARS-CoV-2 rapid serological tests in comparison with WANTAI SARS-CoV-2 ab ELISA in Burkina Faso, West Africa.
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Autor/in / Beteiligte Person: | Ouedraogo, Henri Gautier ; Zoure, Abdou Azaque ; Compaoré, Tegwinde Rebeca ; Ky, Herve ; Zida, Sylvie ; Zingué, Dezemon ; Ouedraogo, Oumarou ; Soubeiga, Serge Théophile ; Sagna, Tani ; Dabiré, Charlemagne ; Kambiré, Dinanibè ; Zongo, Dramane ; Yonli, Albert Théophane ; Nikiema, Abdoul Rahamani ; Nezien, Désiré ; Bansé, Gnintassa Cyrille ; Bicaba, Brice Wilfried ; Perier, Sophie ; Sawadogo, Charles ; Yabre, Zakariya |
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Zeitschrift: | Virology Journal, Jg. 20 (2023-03-30), Heft 1, S. 1-9 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1743-422X (print) |
DOI: | 10.1186/s12985-023-02011-4 |
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