Investigations on the Reactivity of Copper(I) Complexes with a N<subscript>3</subscript>S Thioether Ligand System.
In: European Journal of Inorganic Chemistry, Jg. 26 (2023-02-17), Heft 6, S. 1-11
Online
academicJournal
Zugriff:
In the active site of several copper monooxygenases, thioether residues are coordinated through the sulfur atom, e. g. dopamine‐β‐monooxygenase (DβM). The reaction of dioxygen with a series of copper(I) complexes with thioether groups in tripodal ligands based on either derivatives of tris(2‐pyridylmethyl)amine (TMPA) or a guanidine system were investigated by low‐temperature stopped‐flow measurements. The formation of labile intermediates, an end‐on superoxido complex, and μ‐1,2‐trans‐peroxido copper(II) complexes were spectroscopically detected and a kinetic analysis allowed the calculation of activation parameters for these reactions supporting the postulated mechanism. Most interesting was the finding that replacing the ethyl group in the tren‐guanidine derivative (TMGEt)2(SEtEt)N with a methyl group allowed a dramatic increase in the stability of the formed superoxido copper complex. Measurements with ozone were performed in order to find an alternative way to obtain and stabilize the labile intermediates. [ABSTRACT FROM AUTHOR]
Copyright of European Journal of Inorganic Chemistry is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
Investigations on the Reactivity of Copper(I) Complexes with a N<subscript>3</subscript>S Thioether Ligand System.
|
---|---|
Autor/in / Beteiligte Person: | Rotärmel, Thomas ; Specht, Pascal ; Becker, Jonathan ; Neuba, Adam ; Schindler, Siegfried |
Link: | |
Zeitschrift: | European Journal of Inorganic Chemistry, Jg. 26 (2023-02-17), Heft 6, S. 1-11 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1434-1948 (print) |
DOI: | 10.1002/ejic.202200626 |
Schlagwort: |
|
Sonstiges: |
|