NXY-059: A neuroprotective agent in acute stroke.
In: International Journal of Clinical Practice, Jg. 58 (2004-10-01), Heft 10, S. 964-969
Online
academicJournal
Zugriff:
Free radicals play an important role in secondary processes in ischaemic brain injury. Disodium 4-[(tert-butylimino) methyl] benzene-1,3-disulphonateN-oxide (NXY-059) is a nitrone-based free radical trapping agent. Findings from animal stroke models showed that NXY-059 is a potent neuroprotective agent that has a large window of therapeutic opportunity and long-lasting effects. Therefore, NXY-059 may be used as a monotherapy agent for treatment of acute stroke. NXY-059 may also be used as an adjunct agent to thrombolytic therapy, as it can reduce tissue plasminogen activator-induced haemorrhage in ischaemic stroke. [ABSTRACT FROM AUTHOR]
Copyright of International Journal of Clinical Practice is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Titel: |
NXY-059: A neuroprotective agent in acute stroke.
|
---|---|
Autor/in / Beteiligte Person: | Wang, C.X. ; Shuaib, A. |
Link: | |
Zeitschrift: | International Journal of Clinical Practice, Jg. 58 (2004-10-01), Heft 10, S. 964-969 |
Veröffentlichung: | 2004 |
Medientyp: | academicJournal |
ISSN: | 1368-5031 (print) |
DOI: | 10.1111/j.1368-5031.2004.00245.x |
Schlagwort: |
|
Sonstiges: |
|