Solid phase synthesis of U1 RNA oligomers containing a TMG cap structure.
In: Nucleic acids symposium series, 1997, Heft 37, S. 77
academicJournal
Zugriff:
We report the solid-phase synthesis of a 5'-terminal part of U1 RNA. In this approach, a new method for pyro- and tri-phosphate bond formation on solid supports was studied. Since 2,2,7-trimethyl guanosine (TMG) in the cap structure was unstable under basic conditions, a RNA oligomer was synthesized by using a linker having the P-N bond, which can be cleaved from the solid support by treatment with 80% acetic acid.
Titel: |
Solid phase synthesis of U1 RNA oligomers containing a TMG cap structure.
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Autor/in / Beteiligte Person: | Kadokura, M ; Ushioda, M ; Wada, T ; Sekine, M |
Zeitschrift: | Nucleic acids symposium series, 1997, Heft 37, S. 77 |
Veröffentlichung: | London : Oxford University Press ; <i>Original Publication</i>: [London] ; Information Retrieval Ltd., c1979-c2000., 1997 |
Medientyp: | academicJournal |
ISSN: | 0261-3166 (print) |
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