Cognitive impairment in long-COVID.
In: Ideggyogyaszati szemle, Jg. 77 (2024-05-30), Heft 5-6, S. 151
academicJournal
Zugriff:
Methods: The search methodology used in this review aimed to include a wide range of research on cognitive impairment related to both COVID-19 and long-COVID. Systematic searches of PubMed and Google Scholar databases were conducted using a mixture of MeSH terms and keywords including ‘cognition’, ‘cognitive impairment’, ‘brain fog’, ‘COVID-19’ and ‘long-COVID’. The search was restricted to studies published in English between 1 January 2019 and 11 February 2024, which presented findings on neurological manifestations in human participants. .
Results: Long-COVID is characterized by persistent symptoms following COVID-19 infection, with cognitive impairment being a prominent feature. Symptoms include brain fog, difficulties with concentration, memory issues, and executive function deficits. Pathophysiological mechanisms involve viral persistence, immune responses, and vascular damage. Risk factors include age, pre-existing conditions, and disease severity. Cognitive assessment tools such as the Montreal Cognitive Assessment (MoCA) are essential for diagnosis. Imaging studies, including MRI, PET, and SPECT, reveal structural and functional brain alterations. Potential biomarkers include C-reactive protein, interleukin-6, and neuron-specific enolase. Management strategies encompass cognitive rehabilitation, occupational therapy, medications, and lifestyle modifications. .
Conclusion: Long-COVID poses a multifaceted challenge, and cognitive impairment significantly impacts patients’ lives. A multidisciplinary approach, including cognitive rehabilitation and medication when appropriate, is essential for effective management. Future research should focus on validating biomarkers and understanding long-term cognitive outcomes. Conclusion – Long-COVID is a global health concern, and cognitive impairment is a distressing symptom. While pharmacological interventions have potential, they require careful consideration. Continued research is crucial for improving the understanding and treatment of cognitive impairment in long-COVID. .
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Cognitive impairment in long-COVID.
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Autor/in / Beteiligte Person: | Julide, T ; Cigdem, T ; Baris, T |
Zeitschrift: | Ideggyogyaszati szemle, Jg. 77 (2024-05-30), Heft 5-6, S. 151 |
Veröffentlichung: | <2004- > : Budapest : Literatura Medica ; <i>Original Publication</i>: Budapest, Művelt Nép Tudományos és Ismeretterjesztő Kiadó, 2024 |
Medientyp: | academicJournal |
ISSN: | 0019-1442 (print) |
DOI: | 10.18071/isz.77.0151 |
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