Effect of MSX1 on the cellular function of cardiomyocytes.
In: Gene, Jg. 916 (2024-07-20), S. 148419
Online
academicJournal
Zugriff:
MSX1 (Muscle Segment Homeobox 1) has pleiotropic effects in various tissues, including cardiomyocytes, while the effect of MSX1 on cardiomyocyte cellular function was not well known. In this study, we used AC16 cell culture, real-time fluorescence quantitative PCR (qPCR), protein blotting (Western blot), flow cytometry apoptosis assay and lactate dehydrogenase (LDH) ELISA (Enzyme-Linked Immunosorbnent Assay) to investigate the effect of the MSX1 gene on cardiomyocyte function. The results showed that MSX1 plays a protective role against hypoxia of cardiomyocytes. However, further studies are required to fully understand the role of MSX1 in the regulation of LDH expression in different cell types and under different conditions.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Author(s). Published by Elsevier B.V. All rights reserved.)
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Effect of MSX1 on the cellular function of cardiomyocytes.
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Autor/in / Beteiligte Person: | Linhuan, H ; Liangying, Z ; Shaobin, L ; Caixia, Z ; Danlei, C ; Siqi, H ; Peiming, H ; Shu, K ; Yingjun, X ; Yanmin, L |
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Zeitschrift: | Gene, Jg. 916 (2024-07-20), S. 148419 |
Veröffentlichung: | Amsterdam, Elsevier/North-Holland, 1976-, 2024 |
Medientyp: | academicJournal |
ISSN: | 1879-0038 (electronic) |
DOI: | 10.1016/j.gene.2024.148419 |
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