Assessing the Impact of Genratest on Women With Recurrent Implantation Failure: A Single-Center Study.
In: Cureus, Jg. 16 (2024-01-14), Heft 1, S. e52256
Online
academicJournal
Zugriff:
Objective Recurrent implantation failure (RIF) is a significant challenge in assisted reproduction. Genratest has emerged as a potential tool to identify the displaced window of implantation (WOI). This study aimed to evaluate the impact of this test on the pregnancy outcomes of RIF patients. Methods A retrospective analysis was conducted on 143 RIF patients who were categorized into two groups: the personalized embryo transfer (pET, n=69) group and standard embryo transfer (sET, n=74) group. The main measured outcomes were clinical pregnancy, ongoing pregnancy, miscarriage, and live birth rates. Results Genratest effectively diagnoses the displaced WOI in 90% of RIF patients. The pET group exhibited a higher rate of clinical pregnancy (n=36/69, 52.2%) compared to the sET group (n=35/74, 47.3%), but this difference was not statistically significant (p=0.679). Ongoing pregnancy rates were comparable between the pET (n=28/69, 40.6%) and the sET (n=30/74, 40.5%) groups (p=0.996). Live birth rates showed no statistically significant difference between the two groups (n=26/69, 37.7% versus n=22/74, 29.7%, p=0.407). Miscarriage rates were similar in both groups (n=9/69, 13% versus n=11/74, 14.9%, p=0.942). Conclusions pET based on the results of the Genratest did not show a significant improvement in pregnancy outcomes, including clinical pregnancy, ongoing pregnancy, live birth, or miscarriage rates. Further research is needed to identify the role of Genratest in RIF patients.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2024, Tran et al.)
Titel: |
Assessing the Impact of Genratest on Women With Recurrent Implantation Failure: A Single-Center Study.
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Autor/in / Beteiligte Person: | Tran, HP ; Ly, LT ; Do, VN ; Hoang, TT ; Tran, TT ; Le, HN ; Nguyen, PT ; Nguyen, NA ; Huynh, TN |
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Zeitschrift: | Cureus, Jg. 16 (2024-01-14), Heft 1, S. e52256 |
Veröffentlichung: | Palo Alto, CA : Cureus, Inc., 2024 |
Medientyp: | academicJournal |
ISSN: | 2168-8184 (print) |
DOI: | 10.7759/cureus.52256 |
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