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Introduction: There are some problems in the quality control of Epimedii Folium (leaves of Epimedium brevicornum Maxim.), such as the mixed use of Epimedii Folium from different harvesting periods and regions, incomplete quality evaluation, and time-consuming analysis methods.

Objective: Near-infrared (NIR) spectroscopy was conducted to establish a rapid overall quality evaluation method for Epimedii Folium.

Materials and Methods: Quantitative models of the total solid, moisture, total flavonoid, and flavonol glycoside (Epimedin A, Epimedin B, Epimedin C, Icariin) contents of Epimedii Folium were established by partial least squares regression (PLSR). The root mean square error (RMSE) and correlation coefficient (R) were used to evaluate the performance of models. The qualitative models of Epimedii Folium from different geographic origins and harvest periods were established based on K-nearest neighbor (KNN), back-propagation neural network (BPNN), and random forest (RF). Accuracy and Kappa values were used to evaluate the performance of models. A new multivariable signal conversion strategy was proposed, which combines NIR spectroscopy with the PLSR model to predict the absorbance values of retention time points in the high-performance liquid chromatography (HPLC) fingerprint to obtain the predicted HPLC fingerprint. The Pearson correlation coefficient and cosine coefficient were used to evaluate the similarity between real and predicted HPLC fingerprints.

Results: Qualitative models, quantitative models, and the similarity between real and predicted HPLC fingerprints are satisfactory.

Conclusion: The method serves as a fast and green analytical quality evaluation method of Epimedii Folium and can replace traditional methods to achieve the overall quality evaluation of Epimedii Folium.

Titel:	Holistic quality evaluation method of Epimedii Folium based on NIR spectroscopy and chemometrics.
Autor/in / Beteiligte Person:	Chen, Y ; Zhang, J ; Feng, J ; Chen, W ; Liu, W ; Chen, J ; Ye, J ; Li, W
Link:	Zum Volltext
Zeitschrift:	Phytochemical analysis : PCA, Jg. 35 (2024-06-01), Heft 4, S. 771-785
Veröffentlichung:	Chichester, Sussex, UK : Wiley, c1990-, 2024
Medientyp:	academicJournal
ISSN:	1099-1565 (electronic)
DOI:	10.1002/pca.3327
Schlagwort:	Least-Squares Analysis Plant Leaves chemistry Quality Control Chromatography, High Pressure Liquid methods Spectroscopy, Near-Infrared methods Epimedium chemistry Flavonoids analysis Chemometrics methods
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [Phytochem Anal] 2024 Jun; Vol. 35 (4), pp. 771-785. <i>Date of Electronic Publication: </i>2024 Jan 25. MeSH Terms: Spectroscopy, Near-Infrared* / methods ; Epimedium* / chemistry ; Flavonoids* / analysis ; Chemometrics* / methods ; Least-Squares Analysis ; Plant Leaves / chemistry ; Quality Control ; Chromatography, High Pressure Liquid / methods References: Zhao YD, Zhang RQ, Mu LT, et al. Total flavonoids in Epimedii folium koreanum Nakai alleviated chronic renal failure via promoting AMPK activation. Food Funct. 2022;13(2):904‐919. doi:10.1039/D1FO03494D. ; Zhang YJ, Li JQ, Wang Y, Liang Q. Taxonomy of Epimedium (Berberidaceae) with special reference to Chinese species. Chin Herb Med. 2022;14(1):20‐35. doi:10.1016/j.chmed.2021.12.001. ; Bi ZY, Zhang W, Yan XY. Anti‐inflammatory and immunoregulatory effects of icariin and icaritin. Biomed Pharmacother. 2022;151:113180. doi:10.1016/j.biopha.2022.113180. ; Chen C, Wu MJ, Lei HH, et al. A novel Prenylflavonoid Icariside I ameliorates estrogen deficiency‐induced osteoporosis via simultaneous regulation of osteoblast and osteoclast differentiation. ACS Pharmacol Transl. 2023;6(2):270‐280. doi:10.1021/acsptsci.2c00192. ; Zhang QY, Li TQ, Li ZR, et al. Autocrine activity of extracellular vesicles induced by icariin and its effectiveness in glucocorticoid‐induced injury of bone microvascular endothelial cells. Cells. 2022;11:1921. ; Muneri CW, Afedo SY, Xu YP, Ni GC, Shen QX, Rui R. Icariin impacts molecular changes in estrogen receptors but not other reproductive parameters in female mice. Indian J Anim Res. 2018;53(00):451‐456. doi:10.18805/ijar.B‐822. ; Wang CY, Tian SY, Tang Q, et al. Systematic quality evaluation of Epimedium wushanense T. S. Ying based on two quality control standards: total flavonoid glycosides and epimedin C. Chem Biodivers. 2023;20(3):e202200579. doi:10.1002/cbdv.202200579. ; Yan MZ, Zhang ZL, Liu YZ. Difference analysis of different parts of chicory based on HPLC fingerprint and multi‐component content determination. Chin Herb Med. 2022;14(2):317‐323. doi:10.1016/j.chmed.2022.01.006. ; Li Y, Shen Y, Yao CL, Guo D. Quality assessment of herbal medicines based on chemical fingerprints combined with chemometrics approach: a review. J Pharmaceut Biomed. 2020;185:113215. doi:10.1016/j.jpba.2020.113215. ; Liu CX. Quality study needs innovation. Chin Herb Med. 2021;13(1):1. doi:10.1016/j.chmed.2021.01.002. ; Mark AB, Mukti S, Michael JB, Neil PJP, Steven FV, Sean XL. Quantitative NIR determination of isoflavone and saponin content of ground soybeans. Food Chem. 2020;317:126373. doi:10.1016/j.foodchem.2020.126373. ; Zhang ZY, Hao N, Li SN, et al. Rapid quality assessment of Gentianae Macrophyllae Radix based on near infrared spectroscopy and capillary electrophoresis. Electrophoresis. 2023;44(13‐14):1068‐1079. doi:10.1002/elps.202300029. ; Hao N, Gao X, Li WL. Rapid origin identification of chrysanthemum morifolium using laser‐induced breakdown spectroscopy and chemometrics. Postharvest Biol Tec. 2023;197:112226. doi:10.1016/j.postharvbio.2022.112226. ; Hou YZ, Cai X, Miao PQ, et al. A feasibility research on the application of machine vision technology in appearance quality inspection of Xuesaitong dropping pills. Spectrochim Acta A. 2021;258:119787. doi:10.1016/j.saa.2021.119787. ; Li WL, Cheng ZW, Wang YF. Feasibility research on non‐invasive analysis of Tanreqing injection with near infrared spectroscopy. J Near Infrared Spec. 2012;20(6):667‐674. doi:10.1255/jnirs.1022. ; Li WL, Qu HB. Determination of Total organic carbon and soluble solids contents in Tanreqing injection intermediates with NIR spectroscopy and Chemometrics. Chemometr Intell Lab. 2016;152:140‐145. doi:10.1016/j.chemolab.2015.12.018. ; Li WL, Yan X, Qu HB. Rapid analysis of the Tanreqing injection by near‐infrared spectroscopy combined with least squares support vector machine and Gaussian process modeling techniques. Spectrochim Acta a. 2019;218:271‐280. doi:10.1016/j.saa.2019.03.110. ; Alfian G, Syafrudin M, Fitriyani NL, et al. Utilizing random Forest with iForest‐based outlier detection and SMOTE to detect movement and direction of RFID tags. Future Internet. 2023;15(3):103. doi:10.3390/fi15030103. ; Moraes Ingrid AD, Cruz‐Tirado Luis JP, Barbin DF. Online measurement of carambola (Averrhoa carambola L.) physicochemical properties and estimation of maturity stages using a portable NIR spectrometer. Sci Hortic‐Amsterdam. 2022;304:111263. doi:10.1016/j.scienta.2022.111263. ; Li CT, Chen HZ, Zhang YY, Hong SY, Ai W, Mo LN. Improvement of NIR prediction ability by dual model optimization in fusion of NSIA and SA methods. Spectrochim Acta a. 2022;276:121247. doi:10.1016/j.saa.2022.121247. ; Tadahaya M, Katsuhisa M, Hiroyuki K. Interesting properties of profile data analysis in the understanding and utilization of the effects of drugs:review. Biol Pharm Bull. 2020;43(10):1435‐1442. doi:10.1248/bpb.b20‐00301. ; Häne BG, Jäger K, Drexler HG. The Pearson product‐moment correlation coefficient is better suited for identification of DNA fingerprint profiles than band matching algorithms. Electrophoresis. 1993;14(1):967‐972. doi:10.1002/elps.11501401154. Grant Information: 21372503D S&T Program of Hebei; 22S21904600 Shanghai 2022 "S&T Innovation Action Plan" Biomedical S&T Support Project; 22HHZYSS00004 Science and Technology Project of Haihe Laboratory of Modern Chinese Medicine Contributed Indexing: Keywords: Epimedii Folium; multivariable signal conversion; near‐infrared spectroscopy; quality evaluation Substance Nomenclature: 0 (Flavonoids) ; 110642-44-9 (epimedin C) ; 0 (epimedin A) ; 110623-73-9 (epimedin B) ; VNM47R2QSQ (icariin) Entry Date(s): Date Created: 20240126 Date Completed: 20240605 Latest Revision: 20240605 Update Code: 20240606

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Holistic quality evaluation method of Epimedii Folium based on NIR spectroscopy and chemometrics.