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In 2017, highly fatal canine leptospirosis emerged in Sydney, Australia. Based on results of microscopic agglutination testing (MAT), serovar Copenhageni appeared to be the most common causative serovar. Prior to this, no clinical cases had been reported since 1976. In a serosurvey of healthy dogs in Australian shelters in 2004, 2.4% of 431 New South Wales dogs had serological evidence of exposure to Copenhageni, the most prevalent serovar. The aim of this study was to estimate the current prevalence of Leptospira exposure and associated serovars in healthy Sydney dogs, previously unvaccinated against Leptospira. Serum samples from 411 healthy dogs in leptospirosis hotspots and neighbouring suburbs were collected before vaccination. MAT for 23 serovars was performed at the WHO Leptospirosis Reference Laboratory in Queensland, Australia. The overall seroprevalence was 4.1% (17/411) with low titres (1/50-1/200) detected. Eleven dogs were from known leptospirosis hotspots. Eight dogs were known to hunt rodents. One dog had been in contact with a leptospirosis positive dog 1 year prior. Serovar Topaz was the most prevalent serovar (n = 5) followed by serovars Australis (n = 4), Copenhageni (n = 4), Djasiman (n = 2), Cynopteri (n = 1), Javanica (n = 1), Medanensis (n = 1), and Pomona (n = 1). In conclusion, serological evidence of exposure of dogs in Sydney to Leptospira is low, but apparently has increased since 2004. Positive titres to serovars not previously reported to cause disease in dogs could be due to low virulence of those serovars or cross-reactivity with other serovars.

Titel:	Serological evidence of exposure of healthy dogs to Leptospira in Sydney, New South Wales, Australia.
Autor/in / Beteiligte Person:	Griebsch, C ; Kirkwood, N ; Ward, MP ; Norris, JM
Link:	Zum Volltext
Zeitschrift:	Australian veterinary journal, Jg. 102 (2024-04-01), Heft 4, S. 215-221
Veröffentlichung:	Oxford : Wiley-Blackwell Pub. ; <i>Original Publication</i>: New South Wales : Australian Veterinary Association, 2024
Medientyp:	academicJournal
ISSN:	1751-0813 (electronic)
DOI:	10.1111/avj.13315
Schlagwort:	Animals Dogs New South Wales epidemiology Seroepidemiologic Studies Australia Antibodies, Bacterial Leptospira Leptospirosis epidemiology Leptospirosis veterinary Leptospirosis prevention & control Dog Diseases
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [Aust Vet J] 2024 Apr; Vol. 102 (4), pp. 215-221. <i>Date of Electronic Publication: </i>2024 Jan 14. MeSH Terms: Leptospira* ; Leptospirosis* / epidemiology ; Leptospirosis* / veterinary ; Leptospirosis* / prevention & control ; Dog Diseases* ; Animals ; Dogs ; New South Wales / epidemiology ; Seroepidemiologic Studies ; Australia ; Antibodies, Bacterial References: Reagan KL, Sykes JE. Diagnosis of canine leptospirosis. Vet Clin Small Anim Pract 2019;49:719–731. ; Schuller S, Francey T, Hartmann K et al. European consensus statement on leptospirosis in dogs and cats. J Small Anim Pract 2015;56:159–179. ; Griebsch C, Ward MP, Norris JM. Canine leptospirosis–global distribution, diagnosis, and treatment. 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Leptospirosis serology in the common brushtail possum (Trichosurus vulpecula) from urban Sydney, Australia. J Wildl Dis 2007;43:492–497. Grant Information: Betty and Keith Cook Canine Research Fund; Margo Roslyn Flood Bequest; MSD Australia Contributed Indexing: Keywords: Australia; Leptospira; Leptospirosis; canine; seroprevalence Substance Nomenclature: 0 (Antibodies, Bacterial) Entry Date(s): Date Created: 20240114 Date Completed: 20240403 Latest Revision: 20240403 Update Code: 20240403

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Serological evidence of exposure of healthy dogs to Leptospira in Sydney, New South Wales, Australia.