NIR-responsive injectable magnesium phosphate bone cement loaded with icariin promotes osteogenesis.
In: Journal of the mechanical behavior of biomedical materials, Jg. 150 (2024-02-01), S. 106256
Online
academicJournal
Zugriff:
There were defects like limited osteogenesis and fast drug release in traditional magnesium phosphate bone cement (MPC). In this study, we loaded icariin in a mesoporous nano silica container modified by polydopamine and then added it and citric acid into MPC (IHP-CA MPCs). The results indicate that IHP-CA MPCs have a long curing time, almost neutral pH value, excellent injectability, and compressive strength. In vitro experiments have shown that IHP-CA MPCs have good biocompatibility and bone promoting ability. These improvements provide feasible solutions and references for the clinical application of MPCs as implants.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
| Titel: |
NIR-responsive injectable magnesium phosphate bone cement loaded with icariin promotes osteogenesis.
|
|---|---|
| Autor/in / Beteiligte Person: | Wang, B ; Zhao, Y ; Li, Y ; Tang, C ; He, P ; Liu, X ; Yao, J ; Chu, C ; Xu, B |
| Link: | |
| Zeitschrift: | Journal of the mechanical behavior of biomedical materials, Jg. 150 (2024-02-01), S. 106256 |
| Veröffentlichung: | Amsterdam : Elsevier, 2024 |
| Medientyp: | academicJournal |
| ISSN: | 1878-0180 (electronic) |
| DOI: | 10.1016/j.jmbbm.2023.106256 |
| Schlagwort: |
|
| Sonstiges: |
|