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Objective: To determine if an association between ionized magnesium (iMg) and total magnesium (tMg) exists in healthy and hospitalized dogs admitted through an emergency service and to assess the associations between iMg and tMg with total protein, albumin, ionized calcium, and total calcium.

Design: Prospective cohort study.

Setting: Veterinary teaching hospital.

Animals: Sixty-nine dogs were enrolled. The healthy control group (group 1) included 24 dogs, and the hospitalized group (group 2) included 45 dogs.

Interventions: None.

Measurements and Main Results: For both groups, signalment, a venous blood gas, and serum biochemistry were obtained. In addition, the presumptive diagnosis was recorded for group 2. Blood was obtained prior to any therapeutic interventions. Group 1 tMg was within the reference interval (RI), and the values for iMg were used to provide a healthy group range (HGR) of 0.44-0.50 mmol/L. Group 2 tMg was within the RI, but iMg was below the calculated HGR range (group 2 median iMg = 0.4 mmol/L; range = 0.27-0.70). There was a significant positive correlation between iMg and tMg in each group (group 1: r = 0.6713, P = 0.0003; group 2: r = 0.5312, P = 0.0002). Ionized Mg and tMg were not significantly associated with any of the other evaluated variables in either group.

Conclusions: Ionized Mg and tMg were significantly associated in both healthy and hospitalized dogs, but the relationship was weaker in the hospitalized dogs compared with the healthy population. For hospitalized dogs, the relationship was weak enough to question the validity of using iMg and tMg interchangeably to track magnesium status.

Titel:	Total serum and ionized magnesium concentrations in healthy and hospitalized dogs.
Autor/in / Beteiligte Person:	Murray, ME ; Boiron, L ; Buriko, Y ; Drobatz, K ; Waddell, LS
Link:	Zum Volltext
Zeitschrift:	Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), Jg. 33 (2023-07-01), Heft 4, S. 427-434
Veröffentlichung:	<2005-> : Malden, MA : Blackwell ; <i>Original Publication</i>: San Antonio, TX : Veterinary Emergency & Critical Care Society, [2001]-, 2023
Medientyp:	academicJournal
ISSN:	1476-4431 (electronic)
DOI:	10.1111/vec.13302
Schlagwort:	Humans Dogs Animals Prospective Studies Hospitals, Animal Hospitals, Teaching Electrolytes Magnesium Calcium
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Effect of 1,25-dihydroxyvitamin-D3 on calcium and magnesium absorption in the healthy-human jejunum and ileum. Am J Med. 1983;75:973-976. Contributed Indexing: Keywords: calcium; clinical pathology; critical care; magnesium; small animal Substance Nomenclature: I38ZP9992A (Magnesium) ; SY7Q814VUP (Calcium) ; 0 (Electrolytes) Entry Date(s): Date Created: 20230607 Date Completed: 20231102 Latest Revision: 20231102 Update Code: 20231215

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Total serum and ionized magnesium concentrations in healthy and hospitalized dogs.