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Objective: This study was performed to develop a new diagnostic algorithm for adult-onset Still's disease (AOSD).

Methods: We conducted a multicenter prospective nationwide case-control study in tertiary Internal Medicine, Rheumatology, and Infectious Diseases departments, to include successively patients with suspected AOSD based on the presence of two or more major criteria of Yamaguchi and/or Fautrel classifications. Patients were classified as AOSD or controls according to a predefined procedure. A receiving operating characteristic curve was used to determine the best cutoff value of the points-based score for disease classification. A diagnostic algorithm was developed to help the physician in the diagnostic approach.

Results: A total of 160 patients were included, 80 patients with AOSD and 60 controls with different diagnoses. Twenty patients with incomplete data were excluded. In the multivariate analysis, 6 items remained independently associated with AOSD diagnosis: typical rash (OR: 24.01, 3 points), fever ≥ 39 °C (OR: 17.34, 3 points), pharyngitis (OR: 10.23, 2 points), arthritis (OR: 9.01, 2 points), NLR ≥ 4 (OR: 11.10, 2 points), and glycosylated ferritin ≤ 20% (OR: 1.59, 1 point). AOSD should be considered if the patient satisfies 7 points with a sensitivity of 92.5%, specificity of 93.3%, and accuracy of 92.8% (area under the curve (AUC): 0.97 [95% CI: 0.94-0.99]). The present points-based score was more accurate and sensitive than the Yamaguchi classification (78.8%, 92.5%, p = 0.01) and Fautrel classification (76.3%, 92.5%, p = 0.004). A typical rash associated with a points-based score ≥ 7 points leads to a very likely disease.

Conclusion: The proposed new algorithm could be a good diagnostic tool for adult-onset Still's disease in clinical practice and research. Key Points • A diagnostic algorithm was performed to help the physician in the diagnostic approach of AOSD. • The points-based score included in this algorithm had a high sensitivity and accuracy. • This diagnostic algorithm can be useful in the clinical research.

Titel:	Proposal of a new diagnostic algorithm for adult-onset Still's disease.
Autor/in / Beteiligte Person:	Daghor-Abbaci, K ; Ait Hamadouche, N ; Makhloufi, CD ; Mechid, F ; Otmani, F ; Makrelouf, M ; Otmane, A ; Smail, N ; Boucelma, M ; Aissat, FZ ; Lefkir-Teffiani, S ; Bengana, B ; Boukheris, N ; Tebaibia, A ; Taharbouchet, B ; Ayoub, S ; Benziane, B ; Oumnia, N ; Haouichet, C ; Hanni, F ; Laraba, N ; Hakem, D ; Benfenatki, N ; Berrah, A
Link:	Zum Volltext
Zeitschrift:	Clinical rheumatology, Jg. 42 (2023-04-01), Heft 4, S. 1125-1135
Veröffentlichung:	<2008->: Heidelberg : Springer ; <i>Original Publication</i>: Brussels : Acta Medica Belgica, [1982-, 2023
Medientyp:	academicJournal
ISSN:	1434-9949 (electronic)
DOI:	10.1007/s10067-023-06509-8
Schlagwort:	Adult Humans Case-Control Studies Prospective Studies Algorithms Still's Disease, Adult-Onset diagnosis Still's Disease, Adult-Onset complications Exanthema diagnosis Exanthema complications
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Multicenter Study; Journal Article Language: English [Clin Rheumatol] 2023 Apr; Vol. 42 (4), pp. 1125-1135. <i>Date of Electronic Publication: </i>2023 Jan 25. MeSH Terms: Still's Disease, Adult-Onset* / diagnosis ; Still's Disease, Adult-Onset* / complications ; Exanthema* / diagnosis ; Exanthema* / complications ; Adult ; Humans ; Case-Control Studies ; Prospective Studies ; Algorithms Comments: Comment in: Clin Rheumatol. 2023 Feb 20;:. (PMID: 36802313) References: Feist E, Mitrovic S, Fautrel F (2018) Mechanisms, biomarkers and targets for adult onset Still’s disease. Nat Rev Rheumatol 14(10):603–618. (PMID: 30218025709730910.1038/s41584-018-0081-x) ; Colina M, Zucchini W, Ciancio G, Orzincolo C, Trotta F, Govoni M (2011) The evolution of adult-onset Still’s disease: an observational and comparative study in a cohort of 76 Italian patients. Semin Arthritis Rheum 41:279–285. (PMID: 2137771410.1016/j.semarthrit.2010.12.006) ; Magadur-Joly G, Billaud E, Barrier GH, Pennec YL, Masson C, Renou P (1995) Epidemiology of adult Still’s disease: estimate of the incidence by retrospective study in west France. Ann Rheum dis 54:587–590. (PMID: 7668903100994010.1136/ard.54.7.587) ; Asanuma YF, Mimura T, Tsuboi H, Noma H, Miyoshi F, Yamamoto K (2015) Nationwide epidemiological survery of 169 patients with adult Still’s disease in Japan. Mod Rheumatol 25(3):393–400. (PMID: 2538273010.3109/14397595.2014.974881) ; Evensen KJ, Nossent HC (2006) Epidemiological and outecomes of adult-onset Still’s disease in Northern Norway. Scand J Rheumatol 35:48–51. (PMID: 1646704210.1080/03009740510026616) ; Gerfaud-Valentin M, Jamilloux I, Iwaz J, Sève P (2014) Adult onset Still’s disease. Autoimmun Rev 13:708–712. (PMID: 2465751310.1016/j.autrev.2014.01.058) ; Mitrovic S, Fautrel B (2018) New markers for adult-onset Still’s disease. Joint Bone Spine 85(3):285–293. (PMID: 2852911710.1016/j.jbspin.2017.05.011) ; Daghor-Abbaci K, Ait Hamadouche N, Otmani F et al (2022) Validation of the neutrophil-to-lymphocyte ratio as a new simple biomarker of adult onset Still’s disease. Medicine 101:32. (PMID: 10.1097/MD.0000000000029970) ; Seo JY, Suh CH, Jung JY, Kim AR, Yang JW, Kim HA (2017) The neutrophil to lymphocyte ratio could be a good diagnostic marquer and predictor of relapses in adult onset Still’s disease. Medicine 96:29. (PMID: 10.1097/MD.0000000000007546) ; Forget P, Khalifa C, Defour JP, Latinne D, Van Pel MC, De Kock M (2017) What is the normal value of the neutrophil-to-lymphocyte ratio. Bmc Res Notes 10(1):12. (PMID: 28057051521725610.1186/s13104-016-2335-5) ; Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H et al (1992) Preliminary criteria for classification of adult Still’s disease. J Rheumatol 19:424–430. (PMID: 1578458) ; Fautrel B, Zing E, Golmard JL, LeMoel G, Bissery A, Rioux C et al (2002) Proposal for a newset of classification criteria for adult-onset still disease. Med (Baltimore) 81:194–200. (PMID: 10.1097/00005792-200205000-00003) ; Qin A, Sun J, Gao C, Li C et al (2022) Bibliometrics analysis on the research status and trends of adult-onset Still’s disease: 1921-2021. Front Immunol 13:950641. https://doi.org/10.3389/fimmu.2022.950641. (PMID: 10.3389/fimmu.2022.950641359242519339616) ; Lebrun D, Mestrallet S, Dehoux M, Golmard JL, Granger B, Georgin-Lavialle S (2017) Validation of the Fautrel classification criteria for adult-onset Still’s disease. Semin Arthritis Rheum 47(4):578–585. (PMID: 2876053610.1016/j.semarthrit.2017.07.005) ; Narváez Garcia, Pascual M, De Recalde ML et al (2017) Adult onset Still’s disease with atypical cutaneous manifestations. Medicine 96:11. (PMID: 10.1097/MD.0000000000006318) ; Criado PR, Carvalho JF, Ayabe LA, Clivati Brandt HR, Romiti R, Maruta CW (2012) Urticaria and dermographism in patients with adult-onset Still’s disease. Rheumatol Int 32:2551–2555. (PMID: 2178595810.1007/s00296-011-2025-5) ; Lee JJY, Hsu CK, Liu MF, Chao SC (2012) Evanescent and persistent pruritic eruptions of adult-onset Still disease: a clinical and pathologic study of 36 patients. Semin Arthritis Rheum 42:317–326. (PMID: 2271720410.1016/j.semarthrit.2012.05.003) ; Ruscitti P, Cipriani P, Masedu F, Lacono D, Ciccia F, Liakouli V (2016) Adult onset Still’s disease : evaluation of prognostic tools and validation of the systemic score by analysis of 100 cases from three center. Medicine 14:194. (PMID: 279032645131497) ; Néel A, Wahbi A, Tessoulin B, Boileau J, Carpentier D, Decaux O (2018) Diagnostic and management of lifethreatening adult-onset Still disease: a French nationwide multicenter study and systematic literature review. Crit Care 22:88. (PMID: 29642928589606910.1186/s13054-018-2012-2) ; Cush JJ, Medsger TA, Christy WC, Herbert DC, Cooperstein LA (1987) Adult-onset Still’s disease. Arthritis Rheum 30:186–94. (PMID: 382795910.1002/art.1780300209) ; Calabro JJ, Londino AV (1986) Adult onset Still’s disease. J Rheumatol 13:827–828. (PMID: 3772935) ; Reginato AJ, Schumacher HR, Baker DG, O’Connor CR, Ferreiros J (1987) Adult onset Still’s disease: experience with 23 patients and literature review with emphasis on organ failure. Semin Arthritis Rheum 17:39–57. (PMID: 330693110.1016/0049-0172(87)90015-1) ; Masson C, Le Loet X, Liote F, Dubost JJ, Boissier MC, Perroux-Goumy L et al (1996) Comparative study of 6 types of criteria in adult Still’s disease. J Rheumatol 23:495–497. (PMID: 8832990) ; Jiang L, Wang Z, Dai X, Jin X (2011) Evaluation of clinical measures and different criteria for diagnosis of adult-onset Still’s disease in a Chinese population. J Rheumatol 38:741–746. (PMID: 2128516310.3899/jrheum.100766) ; Crispín JC, Martínez-Baños D, Alcocer-Varela J (2005) Adult-onset Still disease as the cause of fever of unknown origin. Medicine (Baltimore) 84:331–337. (PMID: 1626740810.1097/01.md.0000188009.47085.76) ; Vanderschueren S, Hermans F, De Munter P, Knockaert D (2012) Adult-onset Still’s disease: still a diagnosis of exclusion. A nested case–control study in patients with fever of unknown origin. Clin Exp Rheumatol 30:514–9. (PMID: 22510428) ; Chen P-D, Yu S-L, Chen S, Weng X-H (2012) Retrospective study of 61 patients with adult onset Still’s disease admitted with fever of unknown origin in China. Clin Rheumatol 31:175–181. (PMID: 2177371510.1007/s10067-011-1798-y) ; Gerfaud-Valentin M, Maucort Boulch D, Hot A, Iwaz J, Ninet J, Durieu I, Broussole C, Seve P (2014) Adult onset Still’s disease, manifestations, treatment, outcome, prognostic factor in 57 patients. Medicine 93:91–99. (PMID: 24646465461630910.1097/MD.0000000000000021) ; Pouchot J, Sampalis JS, Beaudet F, Carette S, Décary F, Salusinsky-Sternbach M et al (1991) Adult Still’s disease: manifestations, disease course, and outcome in 62 patients. Medicine (Baltimore) 70:118–136. (PMID: 200577710.1097/00005792-199103000-00004) ; Hofheinz K, Schett G, Manger B (2016) Adult onset Still’s disease associated with malignancy cause or coincidence. Semin Arthritis Rheum 45:621–626. (PMID: 2658148510.1016/j.semarthrit.2015.10.003) ; Lundberg IE, Tjärnlund A, Bottai M et al (2017) 2017 European League Against Rheumatism/American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. Ann Rheum Dis 69:2271–2282. https://doi.org/10.1136/annrheumdis-2017-211468. (PMID: 10.1136/annrheumdis-2017-211468) ; Fardet L, Coppo P, Kettaneh A, Dehoux M, Cabane J, Lambotte O (2008) Low glycosylated ferritin, a good marker for the diagnosis of hemophagocytic syndrome. Arthritis Rheum 58:1521–1527. (PMID: 1843882110.1002/art.23415) ; Nagai Y, Hasegawa M, Okada E, Hattori T, Tago O, Ishikawa O (2012) Clinical follow-up study of adult-onset Still’s disease. J Dermatol 39(898):901. ; Kikuchi N, Satoh M, Ohtsuka M, Yamamoto T (2014) Persistent pruritic papules and plaques associated with adult onset Still’s disease: report of six cases. J Dermatol 41(5):407–410. (PMID: 2462810010.1111/1346-8138.12426) ; Larson AR, Laga AC, Granter SR (2015) The spectrum of histopathologic fundings in cutameous lesions in patients with Still’s disease. Am J Clin Pathol 144(6):945–951. (PMID: 2657300210.1309/AJCPZE77UAPSMDCD) ; Mian M, Fiore CT, Wilder E (2019) Atypical cutaneous and histological presentation of adult-onset Still’s disease. Proc 32(3):422–424. ; Mitrovic S, Feist E, Fautrel B (2020) Adult-onset Still’s disease. In: Cimaz R (ed) Periodic and non-periodic fevers. Rare Diseases of the immune system. A book chapter. Springer, Cham, pp 93–132. https://doi.org/10.1007/978-3-030-19055-2_6. ; Maria T, Le Alain Q, Christian J, Touitou E, Rivière S, Guilpain P (2014) Adult onset Still’s disease (AOSD) in the era of biologic therapies: dichotomous view for cytokine and clinical expressions. Autoimmun Rev 13:1149–1159. (PMID: 2518324410.1016/j.autrev.2014.08.032) ; Hot A, Toh ML, Coppéré B, Perard L, Girard-Madoux MH, Mausservey C et al (2010) Reactive hemophagocytic syndrome in adult-onset Still disease: clinical features and long-term outcome: a case-control study of 8 patients. Medicine (Baltimore) 89:37–46. (PMID: 2007570310.1097/MD.0b013e3181caf100) ; Abbaci-Daghor K, Otmane A, Makrelouf M et al (2021) Prognostic factors in adult onset Still’s disease. Arch Rheum & Arthritis Res 1(5) ARAR.MS.ID.000523. https://doi.org/10.33552/ARAR.2021.01.000523. ; Ak O, Ozer S, Cag Y, Karagoz G (2012) An adult onset Still’s disease mimicking pneumonia. Rheumatol Int 32:2539–2541. (PMID: 2036132910.1007/s00296-010-1445-y) ; Kong X-D, Xu D, Zhang W, Zhao Y, Zeng X, Zhang F (2010) Clinical features and prognosis in adult-onset Still’s disease: a study of 104 cases. Clin Rheumatol 29:1015–9. (PMID: 2054927610.1007/s10067-010-1516-1) ; Gabay C, Fautrel B, Rech B, Spertini F, Feist E, Kötter I (2018) Open-label, multicentre, dose-escalating phase II clinical trial on the safety and efficacy of tadekinig alfa (IL-18BP) in adult-onset Still’s disease. Ann Rheum Dis 77:840–847. (PMID: 29472362) ; Wang MY, Jia JC, Yang CD, Hu QY (2019) Pathogenesis, disease course, and prognosis of adult-onset Still’s disease: an update and review. Chin Med J (Engl) 132(23):2856–2864. https://doi.org/10.1097/CM9.0000000000000538. (PMID: 10.1097/CM9.000000000000053831856058) ; Tan S, Chen Z, Qiu Y et al (2022) Prognostic factors for adult-onset Still disease: a retrospective analysis of 90 patients in China. Eur J Dermatol 32:56–63. (PMID: 3517178610.1684/ejd.2022.4192) ; Tamai H, Kaneko Y, Takeuchi T (2019) Clinical and laboratory features of macrophage activation syndrome in patients with adult Still’s disease. Ann Rheum Dis 78:1003–1004. ; Mehta BY, Ibrahim S, Briggs W, Efthimiou P (2019) Racial/ethnic variations in morbidity and mortality in adult onset Still’s disease: an analysis of national dataset. Semin Arthritis Rheum 49(3):469–473. (PMID: 3110963810.1016/j.semarthrit.2019.04.004) ; Wang R, Li T, Ye S, Tan W, Zhao C, Li Y et al (2020) Macrophage activation syndrome associated with adult-onset Still’s disease: a multicenter retrospective analysis. Clin Rheumatol 39(8):2379–2386. (PMID: 3213057810.1007/s10067-020-04949-0) ; Efthimiou P, Kontizias A, Hur P et al (2021) Adult onset Still’s disease in focus: clinical manifestation, diagnosi, treatment and unmet needs in the era of targeted therapies. Semin Arthritis Rheum 51:858–874. (PMID: 3417579110.1016/j.semarthrit.2021.06.004) ; Bilgin E, Hayran M, Erden A, Armagan B, Sari A, Kilic L et al (2019) Correction to: proposal for a simple algorithm to differentiate adult-onset Still’s disease with other fever of unknown origin causes: a longitudinal prospective study. Clin Rheumatol 38(4):1193–1194. (PMID: 3077886310.1007/s10067-019-04479-4) Contributed Indexing: Keywords: Adult-onset Still’s disease; Classification criteria; Diagnostic algorithm; Glycosylated ferritin; Neutrophil-to-lymphocyte ratio; Typical rash Entry Date(s): Date Created: 20230124 Date Completed: 20230320 Latest Revision: 20230320 Update Code: 20231215

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Proposal of a new diagnostic algorithm for adult-onset Still's disease.