Regulatory mechanism of icariin in cardiovascular and neurological diseases.
In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Jg. 158 (2023-02-01), S. 114156
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Zugriff:
Cardiovascular diseases (CVDs) and neurological diseases are widespread diseases with substantial rates of morbidity and mortality around the world. For the past few years, the preventive effects of Chinese herbal medicine on CVDs and neurological diseases have attracted a great deal of attention. Icariin (ICA), the main constituent of Epimedii Herba, is a flavonoid. It has been shown to provide neuroprotection, anti-tumor, anti-osteoporosis, and cardiovascular protection. The endothelial protection, anti-inflammatory, hypolipidemic, antioxidative stress, and anti-apoptosis properties of ICA can help stop the progression of CVDs and neurological diseases. Therefore, our review summarized the known mechanisms and related studies of ICA in the prevention and treatment of cardio-cerebrovascular diseases (CCVDs), to better understand its therapeutic potential.
Competing Interests: Conflict of interest statement The authors declare that they have no known competing conflicts of interest or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2022 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)
Titel: |
Regulatory mechanism of icariin in cardiovascular and neurological diseases.
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Autor/in / Beteiligte Person: | Wang, Y ; Shang, C ; Zhang, Y ; Xin, L ; Jiao, L ; Xiang, M ; Shen, Z ; Chen, C ; Ding, F ; Lu, Y ; Cui, X |
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Zeitschrift: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Jg. 158 (2023-02-01), S. 114156 |
Veröffentlichung: | Paris : Editions Scientifiques Elsevier ; <i>Original Publication</i>: New York, N.Y. : Masson Pub. USA, Inc., c1982-, 2023 |
Medientyp: | academicJournal |
ISSN: | 1950-6007 (electronic) |
DOI: | 10.1016/j.biopha.2022.114156 |
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