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Background: There are various available therapies for plane warts; however, no specific therapy has been established as entirely effective.

Objective: The aim of work was to assess the effectiveness and safety of topically hydrogen peroxide (HP) 40% solution in treating the plane warts.

Subjects and Methods: The study included 30 patients diagnosed clinically as plane warts. Topical HP 40% was applied with a single-use wood end of a cotton swab soaked with the solution to minimize filtration of effective drug to the surrounding areas. Duration of the treatment was planned to be 4 sessions for each lesion with 2-week interval and a 3-month follow-up period after treatment completion to detect any recurrence.

Results: Complete clearance of plane warts was observed in 27 (90%), and there was no recurrence of the lesions after a 3-month follow-up period.

Conclusion: HP solution especially the 40% concentration may be considered a promising line of treatment for non-genital warts. It is a very effective, safe, cheap, and easy-to-use new topical treatment for non-genital warts.

Titel:	Topical hydrogen peroxide solution 40% in treatment of plane wart.
Autor/in / Beteiligte Person:	Nouh, EAR ; Obaid, ZM ; Aboelwafa, HO
Link:	Zum Volltext
Zeitschrift:	Journal of cosmetic dermatology, Jg. 21 (2022-10-01), Heft 10, S. 4567-4571
Veröffentlichung:	Oxford, UK : Blackwell Science, c2002-, 2022
Medientyp:	academicJournal
ISSN:	1473-2165 (electronic)
DOI:	10.1111/jocd.14766
Schlagwort:	Humans Hydrogen Peroxide adverse effects Treatment Outcome Administration, Topical Condylomata Acuminata drug therapy Warts drug therapy
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [J Cosmet Dermatol] 2022 Oct; Vol. 21 (10), pp. 4567-4571. <i>Date of Electronic Publication: </i>2022 Jan 22. MeSH Terms: Condylomata Acuminata* / drug therapy ; Warts* / drug therapy ; Humans ; Hydrogen Peroxide / adverse effects ; Treatment Outcome ; Administration, Topical References: Sterling JC. Virus infections. In: Burns T, Breatnatch S, Cox N, Griffith C, eds. Rook's Textbook of Dermatology (8th edn). Wiley-Blackwell; 2004:3339-3341. ; Hunter JA, Savin JA, Dahl MV. Clinical Dermatology (4th edn). Blackwell Publishing Company; 2008. ; Vali A, Ferdowsi F. Evaluation of the efficacy of 50% citric acid solution in plane wart treatment. Indian J Dermatol. 2007;52(2):96. ; Seymour S. Peroxygen compounds. In: Seymour S, ed. Disinfection, Sterilization, and Preservation (5th edn). Lea & Febiger; 2000:185-204. ; Murphy EC, Friedman AJ. Hydrogen peroxide and cutaneous 7-biology: translational applications, benefits, and risks. J Am Acad Dermatol. 2019;81(6):1379-1386. ; Hydrogen peroxide 40% (Eskata) for seborrheic keratoses. Med Lett Drugs Ther. 2018;60(1556):157-158. ; Mahran AM, Twisy HO, Elghazally SA, Badran AY. Evaluation of different concentrations of hydrogen peroxide solution (3% and 6%) as a potential new therapeutic option of nongenital warts: a randomized controlled triple-blinded clinical trial. J Cosmet Dermatol. 2020;19(2):416-422. ; Pellegrino M, Trovato E. Photodynamic therapy (PDT). In: Fimiani M, Rubegni P, Cinotti E, eds. Technology in Practical Dermatology. Springer, Cham. 2020: 403-411. ; East Anglian Branch of the Society of Medical Officers of Health. The incidence of warts and plantar warts amongst school children in East Anglia. Med Officer. 1955. ; Massing AM, Epstein WL. Natural history of warts: a two-year study. Arch Dermatol. 1963;87(3):306-310. ; Ghadgepatil SS, Gupta S, Sharma YK. Clinicoepidemiological study of different types of warts. Dermatol Res Pract. 2016;2016:7989817. ; Theng TS, Goh BK, Chong WS, Chan YC, Giam YC. Viral warts in children seen at a tertiary referral centre. Ann Acad Med Singap. 2004;33(1):53-56. ; Bigardi A, Milani M. Successful treatment of molluscum contagiosum skin infection with hydrogen peroxide 1% cream. J Eur Acad Dermatol Venereol. 2003:17:419. ; Schianchi R, Nazzaro G, Veraldi S. Treatment of molluscum contagiosum with hydrogen peroxide. Clin Exp Dermatol. 2018;43(1):66-67. Contributed Indexing: Keywords: Warts; efficacy; hydrogen peroxide; topical treatment Substance Nomenclature: BBX060AN9V (Hydrogen Peroxide) Entry Date(s): Date Created: 20220122 Date Completed: 20221102 Latest Revision: 20221102 Update Code: 20240513

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Topical hydrogen peroxide solution 40% in treatment of plane wart.