THE BRONCHOPULMONARY SYSTEM DAMAGE UNDER THE INFLUENCE OF IONIZING RADIATION EXPOSURE AND RADIONUCLIDES INHALATION IN THE CONDITIONS OF THE CHORNOBYL CATASTROPHE (SUMMARIZING OF 35 YEARS RESEARCH EXPERIENCE).

Sushko, VO ; Shvaiko, LI ; et al.

In: Problemy radiatsiinoi medytsyny ta radiobiolohii, Jg. 26 (2021-12-01), S. 98

academicJournal

The review is devoted to the summarizing of 35 years of research of ionizing radiation exposure and radionuclidesinhalation influence on the bronchopulmonary system of clean-up workers of the Chornobyl NPP accident. Radiationand hygienic preconditions for the formation of chronic respiratory pathology are considered, taking into accountthe dosimetric data of irradiation of the bronchopulmonary system.The main clinical symptoms, features of disorders of pulmonary ventilation capacity and endoscopic forms of lesionsof the bronchopulmonary system of participants in the liquidation of the accident were determined.On the basis of pathomorphological, microbiological and immunological researches the pathomorphosis of chronicnonspecific lung diseases in the conditions of the Chernobyl catastrophe is proved.It is proved that under combined influence of external irradiation and inhalation of a fragmentary mixture ofradionuclides in the condition of the Chernobyl catastrophe, the bronchopulmonary system has become one of themain «targets»-tissues, of realization of stochastic and nonstochastic effects.

(V. O. Sushko, L. I. Shvaiko, K. D. Bazyka, O. V. Apostolova, O. O. Kolosynska.)

Titel:	THE BRONCHOPULMONARY SYSTEM DAMAGE UNDER THE INFLUENCE OF IONIZING RADIATION EXPOSURE AND RADIONUCLIDES INHALATION IN THE CONDITIONS OF THE CHORNOBYL CATASTROPHE (SUMMARIZING OF 35 YEARS RESEARCH EXPERIENCE).
Autor/in / Beteiligte Person:	Sushko, VO ; Shvaiko, LI ; Bazyka, KD ; Apostolova, OV ; Kolosynska, OO
Zeitschrift:	Problemy radiatsiinoi medytsyny ta radiobiolohii, Jg. 26 (2021-12-01), S. 98
Veröffentlichung:	Kyïv : Naukovyĭ t︠s︡entr radiat︠s︡iĭnoï medyt︠s︡yny AMN Ukraïny, 2021
Medientyp:	academicJournal
ISSN:	2313-4607 (electronic)
DOI:	10.33145/2304-8336-2021-26-98-123
Schlagwort:	Adult Case-Control Studies Female Humans Inhalation Exposure adverse effects Male Middle Aged Radiation Injuries etiology Respiratory System Abnormalities etiology Ukraine Chernobyl Nuclear Accident Occupational Exposure adverse effects Radiation Exposure adverse effects Radiation Injuries physiopathology Radiation, Ionizing Radioactive Hazard Release Radioisotopes adverse effects Respiratory System Abnormalities physiopathology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Transliterated Title: URAZhENNIa BRONKhOLEGENEVOÏ SYSTEMY VNASLIDOK VPLYVU IONIZUIuChOGO OPROMINENNIa TA INGALIaTsIĬNOGO NADKhODZhENNIa RADIONUKLIDIV V UMOVAKh ChORNOBYL'S'KOÏ KATASTROFY (UZAGAL'NENNIa DOSVIDU 35 ROKIV DOSLIDZhEN'). Publication Type: Journal Article; Review Language: English; Ukrainian [Probl Radiac Med Radiobiol] 2021 Dec; Vol. 26, pp. 98-123. MeSH Terms: Chernobyl Nuclear Accident* ; Radiation, Ionizing* ; Radioactive Hazard Release* ; Occupational Exposure / adverse effects ; Radiation Exposure / adverse effects ; Radiation Injuries / physiopathology ; Radioisotopes / adverse effects ; Respiratory System Abnormalities / *physiopathology ; Adult ; Case-Control Studies ; Female ; Humans ; Inhalation Exposure / adverse effects ; Male ; Middle Aged ; Radiation Injuries / etiology ; Respiratory System Abnormalities / etiology ; Ukraine Contributed Indexing: Keywords: Chernobyl accident; bronchopulmonary system; influence of ionizing radiation; inhalation of radionuclides; pathomorphosis of diseases ; Local Abstract: [Publisher, Ukrainian] Ogliad prysviachenyĭ uzagal'nenniu 35 rokiv doslidzhen' vplyvu ionizuiuchogo oprominennia ta ingaliatsiĭnogo nad-khodzhennia radionuklidiv na bronkholegenevu systemu uchasnykiv likvidatsiï naslidkiv avariï na Chornobyl's'kiĭAES. Rozglianuti radiatsiĭno-gigiienichni peredumovy formuvannia khronichnoï respiratornoï patologiï z urakhuvanniamdozymetrychnykh danykh oprominennia bronkholegenevoï systemy.Vyznacheni osnovna klinichna symptomatyka, osoblyvosti porushen' ventyliatsiĭnoï spromozhnosti legen' ta endos-kopichni formy urazhennia bronkholegenevoï systemy uchasnykiv likvidatsiï avariï.Na osnovi patomorfologichnykh, mikrobiologichnykh ta imunologichnykh doslidzhen' dovedeno patomorfoz khronichnykhnespetsyfichnykh zakhvoriuvan' legen' v umovakh Chornobyl's'koï katastrofy.Dovedeno, shcho pry kombinovanomu vplyvi zovnishn'ogo oprominennia ta ingaliatsiï oskolkovoï sumishi radionuklidivv umovakh Chornobyl's'koï katastrofy bronkholegeneva systema stala odniieiu z osnovnykh tkanyn-«misheneĭ» re-alizatsiï stokhastychnykh i nestokhastychnykh efektiv. Substance Nomenclature: 0 (Radioisotopes) Entry Date(s): Date Created: 20211229 Date Completed: 20220218 Latest Revision: 20220218 Update Code: 20231215

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