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Introduction: Cerebral venous thrombosis (CVT) is the most common manifestation of vasculo-Behçet's disease and may be superficial and/or deep localization. The aim of our study was to evaluate the clinical and radiological features of CVT associated with Behçet's disease in our population and to compare findings with previous studies.

Materials and Methods: We report a retrospective study of 24 cases of CVT secondary to Behçet's disease, collected between 1999 and 2019 in the neurology department of the Mohamed V Military Hospital (Rabat), the Avicenne Military Hospital (Marrakech) and the Mohamed VI Hospital (Marrakech). The diagnosis of Behçet's disease was made in all cases according to the 2014 International Study Group Criteria for Behçet diseases. Patients received antithrombotic treatment, combined with corticosteroids, in six cases of superficial CVT and with immunosuppressants in cases of deep CVT.

Results: Clinical manifestations were dominated by motor deficit in deep localizations and intracranial hypertension in superficial locations. The diencephalic-mesencephalic syndrome was found in 18 patients, whereas intracranial hypertension (71%) and headache (57%) were the most common presentations of superficial CVT. Unlike previous studies, magnetic resonance angiography and conventional angiography performed in our patients confirmed the predominance of deep venous thrombosis (18 cases), whereas superficial CVT was observed only in six cases.

Discussion: In our series, the benefit of conventional angiography was undeniable, by confirming the diagnosis of basal vein of Rosenthal thrombosis in 75% of our patients. Short-term outcome was favorable, but sequelae of CVT were noted in 20 patients (75%). The outcome of patients was commonly mRS 02, however 70% of patients presenting with deep CVT at the beginning had a poor outcome (mRS 03) and we did not record any case of venous thrombosis relapse.

Titel:	Cerebral venous thrombosis in Behcet's disease. A report on 24 cases.
Autor/in / Beteiligte Person:	Oumerzouk, J ; Klevor, R ; Slioui, B ; Chraa, M ; Louhab, N ; Kissani, N
Link:	Zum Volltext
Zeitschrift:	Revue neurologique, Jg. 178 (2022-03-01), Heft 3, S. 213
Veröffentlichung:	Paris : Masson ; <i>Original Publication</i>: Paris., 2022
Medientyp:	academicJournal
ISSN:	0035-3787 (print)
DOI:	10.1016/j.neurol.2021.05.008
Schlagwort:	Humans Retrospective Studies Behcet Syndrome complications Behcet Syndrome diagnosis Behcet Syndrome drug therapy Cerebral Veins diagnostic imaging Intracranial Thrombosis diagnostic imaging Intracranial Thrombosis etiology Venous Thrombosis diagnosis Venous Thrombosis drug therapy Venous Thrombosis etiology
Sonstiges:	Nachgewiesen in: MEDLINE Sprachen: English Publication Type: Journal Article Language: English [Rev Neurol (Paris)] 2022 Mar; Vol. 178 (3), pp. 213-218. <i>Date of Electronic Publication: </i>2021 Sep 23. MeSH Terms: Behcet Syndrome* / complications ; Behcet Syndrome* / diagnosis ; Behcet Syndrome* / drug therapy ; Cerebral Veins* / diagnostic imaging ; Intracranial Thrombosis* / diagnostic imaging ; Intracranial Thrombosis* / etiology ; Venous Thrombosis* / diagnosis ; Venous Thrombosis* / drug therapy ; Venous Thrombosis* / etiology ; Humans ; Retrospective Studies Contributed Indexing: Keywords: Behçet; MRI; Thrombosis; Venous Entry Date(s): Date Created: 20210926 Date Completed: 20220406 Latest Revision: 20220406 Update Code: 20240513

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Cerebral venous thrombosis in Behcet's disease. A report on 24 cases.