IL-6 and other biomarkers as predictors of severity in COVID-19.
In: Annals of medicine, Jg. 53 (2021-12-01), Heft 1, S. 410
Online
academicJournal
Zugriff:
Objective: Cytokine release syndrome is suggested to be the most important mechanism triggering acute respiratory distress syndrome and end organ damage in COVID-19. The severity of disease may be measured by different biomarkers.
Methods: We studied markers of inflammation and coagulation as recorded in 29 patients on admission to the hospital in order to identify markers of severe COVID-19 and need of ICU.
Results: Patients who were eventually admitted to ICU displayed significantly higher serum levels of interleukin-6 (IL-6), C-reactive protein (CRP), and procalcitonin. No statistical differences were found between the groups in median levels of lymphocytes, D-dimer or ferritin.
Conclusions: IL-6 and CRP were the strongest predictors of severity in hospitalized patients with COVID-19.
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IL-6 and other biomarkers as predictors of severity in COVID-19.
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Autor/in / Beteiligte Person: | Broman, N ; Rantasärkkä, K ; Feuth, T ; Valtonen, M ; Waris, M ; Hohenthal, U ; Rintala, E ; Karlsson, A ; Marttila, H ; Peltola, V ; Vuorinen, T ; Oksi, J |
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Zeitschrift: | Annals of medicine, Jg. 53 (2021-12-01), Heft 1, S. 410 |
Veröffentlichung: | London : Informa Healthcare ; <i>Original Publication</i>: Helsinki : Finnish Medical Society Duodecim, 1989-, 2021 |
Medientyp: | academicJournal |
ISSN: | 1365-2060 (electronic) |
DOI: | 10.1080/07853890.2020.1840621 |
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