Icariin and its metabolites regulate lipid metabolism: From effects to molecular mechanisms.
In: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Jg. 131 (2020-11-01), S. 110675
Online
academicJournal
Zugriff:
Icariin has a variety of biological activities, such as lipid-lowering effects, and has attracted widespread attention in recent years. However, it is not clear whether lipid-lowering effect is that multiple metabolites or a particular component plays a major role. It is known that icariin has a variety of metabolites in the body, including icariside I, icariside II, icaritin, desmethylicaritin, and other metabolites. Many of these studies have shown that the metabolites of icariin have a lipid-lowering effect. This paper focuses on the lipid-regulating effects of icariin and its metabolites in vitro and in vivo, and highlights the mechanisms involved. Icariin may have potential in the development of therapeutic strategies to regulate lipid metabolism.
(Copyright © 2020 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.)
| Titel: |
Icariin and its metabolites regulate lipid metabolism: From effects to molecular mechanisms.
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| Autor/in / Beteiligte Person: | Wang, M ; Gao, H ; Li, W ; Wu, B |
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| Zeitschrift: | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, Jg. 131 (2020-11-01), S. 110675 |
| Veröffentlichung: | Paris : Editions Scientifiques Elsevier ; <i>Original Publication</i>: New York, N.Y. : Masson Pub. USA, Inc., c1982-, 2020 |
| Medientyp: | academicJournal |
| ISSN: | 1950-6007 (electronic) |
| DOI: | 10.1016/j.biopha.2020.110675 |
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