Evaluation of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of KPC-Producing Klebsiella pneumoniae.
In: Journal of clinical microbiology, Jg. 54 (2016-10-01), Heft 10, S. 2609
Online
academicJournal
Zugriff:
We evaluated a real-time single-peak (11.109-Da) detection assay based on matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) for the identification of Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae Our results demonstrated that the 11.109-Da peak was detected in 88.2% of the KPC producers. Analysis of blaKPC-producing K. pneumoniae showed that the gene encoding the 11.109-Da protein was commonly (97.8%) associated with the Tn4401a isoform.
(Copyright © 2016, American Society for Microbiology. All Rights Reserved.)
Titel: |
Evaluation of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of KPC-Producing Klebsiella pneumoniae.
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Autor/in / Beteiligte Person: | Gaibani, P ; Galea, A ; Fagioni, M ; Ambretti, S ; Sambri, V ; Landini, MP |
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Zeitschrift: | Journal of clinical microbiology, Jg. 54 (2016-10-01), Heft 10, S. 2609 |
Veröffentlichung: | Washington, American Society for Microbiology., 2016 |
Medientyp: | academicJournal |
ISSN: | 1098-660X (electronic) |
DOI: | 10.1128/JCM.01242-16 |
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