Synergistically killing activity of aspirin and histone deacetylase inhibitor valproic acid (VPA) on hepatocellular cancer cells.
In: Biochemical & Biophysical Research Communications, Jg. 436 (2013-06-28), Heft 2, S. 259-264
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Zugriff:
Highlights: [•] Novel combination therapy using aspirin and valproic acid (VPA). [•] Combination of aspirin and VPA elicits synergistic cytotoxic effects. [•] Combination of aspirin and VPA significantly reduces the drug dosage required alone. [•] Combination of aspirin and VPA significantly inhibit tumor growth. [•] Lower dose of aspirin in combination therapy will minimize side effects of aspirin. [ABSTRACT FROM AUTHOR]
Titel: |
Synergistically killing activity of aspirin and histone deacetylase inhibitor valproic acid (VPA) on hepatocellular cancer cells.
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Autor/in / Beteiligte Person: | Li, Xiaofei ; Zhu, Yanshuang ; He, Huabin ; Lou, Lianqing ; Ye, Weiwei ; Chen, Yongxin ; Wang, Jinghe |
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Zeitschrift: | Biochemical & Biophysical Research Communications, Jg. 436 (2013-06-28), Heft 2, S. 259-264 |
Veröffentlichung: | 2013 |
Medientyp: | academicJournal |
ISSN: | 0006-291X (print) |
DOI: | 10.1016/j.bbrc.2013.05.088 |
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