Ozone oxidation of antidepressants in wastewater –Treatment evaluation and characterization of new by-products by LC-QToFMS.
In: Chemistry Central Journal, Jg. 7 (2013-03-01), Heft 1, S. 1-11
Online
academicJournal
Zugriff:
Background: The fate of 14 antidepressants along with their respective N-desmethyl metabolites and the anticonvulsive drug carbamazepine was examined in a primary sewage treatment plant (STP) and following advanced treatments with ozone (O3). The concentrations of each pharmaceutical compound were determined in raw sewage, effluent and sewage sludge samples by LC-MS/MS analysis. The occurrence of antidepressant by-products formed in treated effluent after ozonation was also investigated. Results: Current primary treatments using physical and chemical processes removed little of the compounds (mean removal efficiency: 19%). Experimental sorption coefficients (Kd) of each studied compounds were also calculated. Sorption of venlafaxine, desmethylvenlafaxine, and carbamazepine on sludge was assumed to be negligible (log Kd ≤ 2), but higher sorption behavior can be expected for sertraline (log Kd ≥ 4). Ozonation treatment with O3 (5 mg/L) led to a satisfactory mean removal efficiency of 88% of the compounds. Screening of the final ozone-treated effluent samples by high resolution-mass spectrometry (LC-QqToFMS) did confirm the presence of related N-oxide by-products. Conclusion: Effluent ozonation led to higher mean removal efficiencies than current primary treatment, and therefore represented a promising strategy for the elimination of antidepressants in urban wastewaters. However, the use of O3 produced by-products with unknown toxicity. [ABSTRACT FROM AUTHOR]
Titel: |
Ozone oxidation of antidepressants in wastewater –Treatment evaluation and characterization of new by-products by LC-QToFMS.
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Autor/in / Beteiligte Person: | Lajeunesse, André ; Blais, Mireille ; Barbeau, Benoît ; Sauvé, Sébastien ; Gagnon, Christian |
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Zeitschrift: | Chemistry Central Journal, Jg. 7 (2013-03-01), Heft 1, S. 1-11 |
Veröffentlichung: | 2013 |
Medientyp: | academicJournal |
ISSN: | 1752-153X (print) |
DOI: | 10.1186/1752-153X-7-15 |
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