Breast Cancer VPAC1 Receptors.
In: Annals of the New York Academy of Sciences, Jg. 1070 (2006-07-01), Heft 1, S. 436-439
Online
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Zugriff:
VIP receptors were investigated in breast cancer biopsy specimens. Twenty biopsy specimens bound 125I-VIP with high affinity. Also, each of the 20 biopsy specimens had high amounts of VPAC1 receptor mRNA. MCF-7 cells have VPAC1 receptors that bound the VIP chemotherapeutic conjugate, (Ala2,8,9,19,24,25,27 Nle17, Lys28)VIP-L2-camptothecin, with high affinity. VIP chemotherapeutic conjugates may be useful agents to inhibit the growth of breast cancer. [ABSTRACT FROM AUTHOR]
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Breast Cancer VPAC1 Receptors.
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Autor/in / Beteiligte Person: | MOODY, TERRY W. ; JENSEN, ROBERT T. |
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Zeitschrift: | Annals of the New York Academy of Sciences, Jg. 1070 (2006-07-01), Heft 1, S. 436-439 |
Veröffentlichung: | 2006 |
Medientyp: | academicJournal |
ISSN: | 0077-8923 (print) |
DOI: | 10.1196/annals.1317.058 |
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