The establishment of Neisseria meningitidis serogroup W135 of the clonal complex ET-37/ST-11 as an epidemic clone and the persistence of serogroup A isolates in Burkina Faso
In: Microbes & Infection, Jg. 7 (2005-04-01), Heft 4, S. 645-649
Online
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Zugriff:
Abstract: We analyzed 48 invasive isolates of Neisseria meningitidis that were isolated from meningitis cases in Burkina Faso (April 2002 to April 2003). Thirty-nine of these isolates had the phenotype (serogroup:serotype:serosubtype) W135:2a:P1.5,2, eight isolates were A:4:P1.9 and one isolate was nongroupable:nonserotypable:nonserosubtypable. Genotyping of meningococcal isolates showed that W135 isolates belonged to the sequence type (ST)-11. The nongroupable isolate was of genogroup W135 and belonged to ST-192. Isolates of serogroup A belonged to ST-2859 (a member of the subgroup III/ST-5 clonal complex). W135 (ST-11) isolates involved in meningitis outbreaks in Burkina Faso differed from those involved in the Hajj-2000 associated outbreak by their pulsed-field gel electrophoresis profile. These data confirm the changing epidemiology of meningococcal infection in Burkina Faso with the establishment and expansion of serogroup W135 N. meningitidis strains of the ET-37/ST-11 clonal complex, as well as the emergence of a new clone within the subgroup III/ST-5 clonal complex. [Copyright &y& Elsevier]
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The establishment of Neisseria meningitidis serogroup W135 of the clonal complex ET-37/ST-11 as an epidemic clone and the persistence of serogroup A isolates in Burkina Faso
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Autor/in / Beteiligte Person: | Njanpop-Lafourcade, Berthe-Marie ; Parent du Châtelet, Isabelle ; Sanou, Oumar ; Alonso, Jean-Michel ; Taha, Muhamed-Kheir |
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Zeitschrift: | Microbes & Infection, Jg. 7 (2005-04-01), Heft 4, S. 645-649 |
Veröffentlichung: | 2005 |
Medientyp: | academicJournal |
ISSN: | 1286-4579 (print) |
DOI: | 10.1016/j.micinf.2005.01.003 |
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