A retrospective cohort study on the cost-effectiveness analysis of kidney transplantation compared to dialysis in Cameroon: evidence for policy.
In: Pan African Medical Journal, Jg. 46 (2023-09-01), S. 1-15
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Zugriff:
Introduction: chronic kidney disease affects one in ten adults in Cameroon. Haemodialysis was the only renal replacement therapy (for adults) in Cameroon and its sub-region until November 10, 2021. Thereafter through May 2022, the Yaoundé General Hospital successfully completed four living-donor kidney transplants. This paper examines policy implications. Methods: medical records of cohorts of kidney failure patients who started haemodialysis at Yaoundé General Hospital in 2012 (n=106) and 2017 (n=118) were abstracted retrospectively through 2021 and their survival analyzed with Microsoft Excel and Kaplan-Meier curves. Using hospital data, the literature, and price indexes, the annual medical cost per patient of dialysis and living-donor kidney transplantation in 2022 prices was derived. Results: the 9.5-year survival rate for the 2012 cohort was 11% and the 5-year rate for the 2017 cohort was 18%. Annual haemodialysis cost per patient averaged $17,681 (26.5% from households and 73.5% from government). Initial transplantation costs averaged $10,530 per patient, all borne by the government. Under the brand-drug option, first-year transplantation follow-up costs $19,070 (4% for laboratory and 96% for drugs). Conclusion: annually, haemodialysis in Cameroon costs per patient 12 times the country's average income ($1,537), driven especially by the costs of equipment purchase, maintenance, and consumables. Cameroon's initial cost of transplantation is lower than in other African countries. Generic drugs could lower annual follow-up costs by 89%. If Cameroon could achieve long-term survival with generic drugs after kidney transplantation, that modality would become a reasonable option for selected kidney failure patients (e.g. younger and without other comorbidities). [ABSTRACT FROM AUTHOR]
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A retrospective cohort study on the cost-effectiveness analysis of kidney transplantation compared to dialysis in Cameroon: evidence for policy.
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Autor/in / Beteiligte Person: | Njamnshi, Rene Kanjo ; Maimouna, Mahamat ; Ngarka, Leonard ; Nono Tomta, Aristide Eric ; Njamnshi, Wepnyu Yembe ; Ashuntantang, Gloria Enow ; Nguemaleu Djientcheu, Vincent de Paul ; Njamnshi, Alfred Kongnyu ; Shepard, Donald Sloane |
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Zeitschrift: | Pan African Medical Journal, Jg. 46 (2023-09-01), S. 1-15 |
Veröffentlichung: | 2023 |
Medientyp: | academicJournal |
ISSN: | 1937-8688 (print) |
DOI: | 10.11604/pamj.2023.46.27.38706 |
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