Cycloartane-type triterpenoids from the whole plants of Macrosolen bidoupensis.
In: Journal of Asian Natural Products Research, Jg. 24 (2022-06-01), Heft 6, S. 596-602
Online
academicJournal
Zugriff:
One new cycloartane-type triterpenoid, named macrobidoupoic acid A (as an C-24 epimeric mixture, 4a, 4 b), together with three known ones (1-3), were clarified by different chromatography from the M. bidoupensis whole plants. Triterpenoids (1, 3 & 4) were detected for the first time from the Macrosolen genus. Chemical structures of them were illuminated using HR-ESI-MS, and NMR (1 D & 2 D) assessments. The cytotoxic properties of triterpenoids (3 & 4) were examined against two human cancer cell lines (A549, and RD) by MTT assay. As results shown, triterpenoids (3 & 4) possessed moderate cytotoxic activity against A549 and RD cancer cells (IC50 ranged from 5.44 to 39.52 μM). [ABSTRACT FROM AUTHOR]
| Titel: |
Cycloartane-type triterpenoids from the whole plants of Macrosolen bidoupensis.
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| Autor/in / Beteiligte Person: | Le, Kieu Hung ; Huynh, Bui Linh Chi ; Pham, Nguyen Kim Tuyen ; Do, Thi Hong Tuoi ; Nguyen, Le Thanh Tuyen ; Dang, Van Son ; Ngo, Quoc Luan ; Tran, Thi Ngoc Mai ; Bui, Trong Dat ; Phan, Nhat Minh ; Mai, Dinh Tri ; Nguyen, Tan Phat |
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| Zeitschrift: | Journal of Asian Natural Products Research, Jg. 24 (2022-06-01), Heft 6, S. 596-602 |
| Veröffentlichung: | 2022 |
| Medientyp: | academicJournal |
| ISSN: | 1028-6020 (print) |
| DOI: | 10.1080/10286020.2021.1949301 |
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