Primary Sjögren's syndrome in men: clinical and immunological characteristics.
In: Lupus, Jg. 9 (2000), Heft 1, S. 61-64
Online
academicJournal
Zugriff:
Objective: To determine the clinical and immunological characteristics of primary Sjögren's syndrome (SS) in men from a large series of unselected patients with this condition. Methods: We studied 223 consecutive patients (204 women and 19 men; mean age at onset 53 y, range 15–87 y, mean disease duration 77 months) with primary SS visited in our units. All these patients fulfilled 4 or more of the diagnostic criteria for SS proposed by the European Community Study Group in 1993. Results: Nineteen (9%) patients were men and they represent the male group described in this paper. Extraglandular manifestations during the course of their disease were present in 10 (53%) of our male patients with primary SS: articular involvement in 4 (21%) patients, interstitial pneumopathy in 3 (16%) and peripheral neuropathy in 2 (11%). ANA were positive in 13 (68%) patients, RF in 5 (31%), anti-Ro/SS-A in 3 (16%) and cryoglobulins in 1/14 (7%). When compared with women, men with primary SS presented a lower prevalence of articular involvement (21% ; vs 46%, P=0.03, OR 0.32, CI 0.07–0.97). Conclusion: Although primary SS is typically a disease of middle-aged women, clinicians should note that it may be diagnosed in male patients. Except for a lower prevalence of articular involvement, we could no find any notable differences in clinical and immunological characteristics between male and female patients with primary SS. Lupus (2000) 9, 61–64 [ABSTRACT FROM AUTHOR]
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Primary Sjögren's syndrome in men: clinical and immunological characteristics.
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Autor/in / Beteiligte Person: | Cervera, Ricard ; Font, Josep ; Ramos-Casals, Manuel ; Garcia-Carrasco, Mario ; Rosas, José ; Morla, Rosa M ; Muñoz, Francisco J. ; Artigues, Antonia ; Pallarés, Lucio ; Ingelmo, Miguel |
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Zeitschrift: | Lupus, Jg. 9 (2000), Heft 1, S. 61-64 |
Veröffentlichung: | 2000 |
Medientyp: | academicJournal |
ISSN: | 0961-2033 (print) |
DOI: | 10.1177/096120330000900111 |
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