Asymmetric sequential double Michael reactions of γ,δ-unsaturated β-ketoesters to nitroolefins catalyzed by Ni (II)-diamine complex.
In: Catalysis Communications, Jg. 102 (2017-12-01), S. 67-70
Online
academicJournal
Zugriff:
The asymmetric sequential double Michael reactions of γ , δ -unsaturated β -ketoesters and nitroolefins catalyzed by 2 mol% of readily prepared Ni(II)-bis[( R , R )- N , N ′-dibenzylcyclohexane-1,2-diamine] complex and then with 1 equivalent of tetramethylguanidine (TMG) for cyclization have been developed. The reaction gave the corresponding Michael adducts of multifunctional cyclohexenol derivatives with three chiral stereocenters in good yields, moderate diastereoselectivities, and high enantioselectivities under mild reaction conditions. [ABSTRACT FROM AUTHOR]
Titel: |
Asymmetric sequential double Michael reactions of γ,δ-unsaturated β-ketoesters to nitroolefins catalyzed by Ni (II)-diamine complex.
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Autor/in / Beteiligte Person: | Huang, Shengying ; Scherer, Karen ; Ni, Bukuo |
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Zeitschrift: | Catalysis Communications, Jg. 102 (2017-12-01), S. 67-70 |
Veröffentlichung: | 2017 |
Medientyp: | academicJournal |
ISSN: | 1566-7367 (print) |
DOI: | 10.1016/j.catcom.2017.08.024 |
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