Discordant Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome in identical twins – a case report and implications for reproduction in MRKH women.
In: Gynecological Endocrinology, Jg. 31 (2015-09-01), Heft 9, S. 684-687
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Zugriff:
Infertility has previously been considered as an inevitable consequence of Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. With modern assisted reproductive technology (ART) techniques becoming increasingly accessible, MRKH women have the opportunity for their own genetic offspring. The availability of such technology, however, increases the importance of understanding the aetiology of this complex condition. The literature debating the relevance of genetic versus post-zygotic events in the aetiology of MRKH syndrome is reviewed in the context of this report of monozygotic twins discordant for MRKH syndrome. 不孕不育曾被认为是先天性子宫阴道缺如(MRKH)综合征的必然结局。随着现代辅助生殖技术(ART)日渐成熟,MRKH综合征妇女有机会繁育自己的后代。然而,这种技术的实用性也引起了对于该病复杂病因的重视。文献中关于MRKH综合征遗传与合子后事件相关病因学的报道存在争议,而本文也对单卵双胎中非协调性先天性子宫阴道缺如(MRKH)综合征的个案进行了报道。 [ABSTRACT FROM PUBLISHER]
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Discordant Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome in identical twins – a case report and implications for reproduction in MRKH women.
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Autor/in / Beteiligte Person: | Milsom, Stella Ruth ; Ogilvie, Cara Megan ; Jefferies, Craig ; Cree, Lynsey |
Zeitschrift: | Gynecological Endocrinology, Jg. 31 (2015-09-01), Heft 9, S. 684-687 |
Veröffentlichung: | 2015 |
Medientyp: | academicJournal |
ISSN: | 0951-3590 (print) |
DOI: | 10.3109/09513590.2015.1032928 |
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