Infants with viral bronchiolitis demonstrate two distinct patterns of nocturnal oxyhaemoglobin desaturation.
In: Acta Paediatrica, Jg. 104 (2015-03-01), Heft 3, S. e106- (6S.)
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Zugriff:
Aim This study aimed to demonstrate that viral bronchiolitis is associated with intermittent oxygen saturation of haemoglobin (SpO2) drops (≥3%) and low basal SpO2 between episodes of haemoglobin desaturation. Methods Infants with bronchiolitis underwent pulse oximetry during the first night following hospital admission and a subgroup of them underwent repeat oximetry before hospital discharge. Oximetry was also performed in infants with partial upper airway obstruction ( UAO) and without lung disease and in control participants without UAO or lung disease. Results We enrolled 53 infants: 21 with bronchiolitis, 11 with UAO and 21 healthy controls. Participants with bronchiolitis had lower basal SpO2 (median 93.7% [10th-90th percentiles: 91.1-96.8]) than the subjects with UAO (96.9% [95.3-98.1]; p < 0.01) or the controls (98.7% [96.9-99.3]; p < 0.01). The bronchiolitis group was not different from the UAO group regarding the desaturation index (23.3 episodes/hour [10.3-46.6] and 15.5 episodes/hour [5.4-36.4], respectively; p = 0.08), but differed significantly from the controls (3.1 episodes/hour [0.3-5.5]; p < 0.01). The basal SpO2 and desaturation index improved in 10 subjects with bronchiolitis who had follow-up oximetry before discharge, but these indices remained abnormal when compared to values in the control group. Conclusion Bronchiolitis was characterised by low nocturnal basal SpO2 and intermittent SpO2 drops. [ABSTRACT FROM AUTHOR]
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Infants with viral bronchiolitis demonstrate two distinct patterns of nocturnal oxyhaemoglobin desaturation.
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Autor/in / Beteiligte Person: | Kaditis, Athanasios G. ; Katsouli, Georgia ; Malakasioti, Georgia ; Kaffe, Katerina ; Gemou‐Engesaeth, Vasiliki ; Alexopoulos, Emmanouel I. |
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Zeitschrift: | Acta Paediatrica, Jg. 104 (2015-03-01), Heft 3, S. e106- (6S.) |
Veröffentlichung: | 2015 |
Medientyp: | academicJournal |
ISSN: | 0803-5253 (print) |
DOI: | 10.1111/apa.12896 |
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