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205 Treffer

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  1. Detailansicht für Treffer 41 öffnen
    https://goketogenics.com/mxm-ultra-force/
    Menzies
    2021
    academicJournal
    Wie komme ich dran?
  2. Detailansicht für Treffer 42 öffnen
    MXM: Feature Selection (Including Multiple Solutions) and BayesianNetworks
    Tsagris, Michail ; Tsamardinos, Ioannis
    2019
    Online Elektronische Ressource
    Wie komme ich dran?
  3. Detailansicht für Treffer 43 öffnen
    MXM: Feature Selection (Including Multiple Solutions) and Bayesian Networks
    Tsagris, Michail
    2019
    Online Elektronische Ressource
    Wie komme ich dran?
  4. Detailansicht für Treffer 44 öffnen
    MXM: Feature Selection (Including Multiple Solutions) and BayesianNetworks
    Tsagris, Michail
    2019
    Online Elektronische Ressource
    Wie komme ich dran?
  5. Detailansicht für Treffer 45 öffnen
    MXM: Feature Selection (Including Multiple Solutions) and Bayesian Networks
    Tsagris, Michail ; Tsamardinos, Ioannis ; et al.
    2018
    Online Elektronische Ressource
    Wie komme ich dran?
  6. Detailansicht für Treffer 46 öffnen
    Figure 4. Genetic epistasis between the H3 tails. ; (A–B) We constructed 12 sets of point mutations in histone H3, with each mutant cycle including H3Xmut/H3Ywt, H3Xwt/H3Ymut, and H3Xmut/H3Ymut – for each mutant trio, X/Y/double mutations are ordered from left to right, as indicated with green/yellow/blue boxes in Panel (B). For all 12 trios, as well as the matched ‘pseudo-wt’ (labeled as pWT) carrying H3Xwt/H3Ywt (leftmost bar and dashed line), we measured doubling times in at least six replicate cultures in low (A) and high (B) KCl. Boxes emphasize H3K14R and H3K36Q trios, as detailed in text. Note that growth rates here were measured robotically in a 96-well format, so doubling times are slower than those typically measured in well-aerated cultures (Figure 4—figure supplement 1A). (C) Effects of H3K36Q mutants on DNA damage sensitivity. Serial dilutions of the indicated strains were plated on YPD, YPD + 10 ng/ml phleomycin or YPD + 0.025% MMS, as indicated. pWT XY (PKY4704), K36Q mXY (PKY4829), K36Q XmY (PKY4831), K36Q mXmY (PKY4834), K36Q_X/P38V_Y (PKY5138), and P38V_X/K36Q_Y (PKY5140). (D–F) Serial dilution growth assay for the indicated strains incubated at 30 C or 34 C, as indicated. Note that yeast carrying pseudo-wild type H3X/H3Y nucleosomes grow poorly at 37C, so we assayed temperature sensitivity at 34 C. Mutant set in (D) shows temperature-sensitivity is specific to symmetric H3K36Q mutant. Mutant set in (E) shows that complete loss of H3K36me3 in the symmetric H3P38V mutant (where H3K36me3 is replaced with H3K36me2) is compatible with rapid growth at high temperatures. Mutant set in (F) shows that a single dimethylated K36 residue per nucleosome is compatible with rapid growth at high temperatures. Strains analyzed were: pWT XY (PKY4704), R2K mXY (PKY4749), R2K XmY (PKY4751), R2K mXmY (PKY4753), K9Q mXY (PKY4714), K9Q XmY (PKY4715), K9Q mXmY (PKY4706), K9R mXY (PKY4773), K9R XmY (PKY4775), K9R mXmY (PKY4777), S10A mXY (PKY4716), S10A XmY (PKY4717), S10A mXmY (PKY4707), K14Q mXY (PKY4789), K14Q XmY (PKY4791), K14Q mXmY (PKY4793), K14R mXY (PKY4781), K14R XmY (PKY4783), K14R mXmY (PKY4786), K18Q mXY (PKY4805), K18Q XmY (PKY4807), K18Q mXmY (PKY4809), K18R mXY (PKY4797), K18R XmY (PKY4799), K18R mXmY (PKY4801), K27Q mXY (PKY4822), K27Q XmY (PKY4823), K27Q mXmY (PKY4825), K27R mXY (PKY4813), K27R XmY (PKY4815), K27R mXmY (PKY4817), K36Q mXY (PKY4829), K36Q XmY (PKY4831), K36Q mXmY (PKY4834), K37Q mXY (PKY4837), K37Q XmY (PKY4839), K37Q mXmY (PKY4841), P38V mXY (PKY5033), P38V XmY (PKY5035), P38V mXmY (PKY5037), K36Q mX/P38V mY (PKY5138), and P38V mX/K36Q mY (PKY5140). pWT XY, pseudo WT; mXY, mutation on X; XmY, mutation on Y; and mXmY, mutation on both X and Y.
    2017
    unknown
    Wie komme ich dran?
  7. Detailansicht für Treffer 47 öffnen
    Figure 4—figure supplement 3. H3P38V mutations block trimethylation but not dimethylation of H3K36. ; Whole cell extracts of the indicated strains were separated by 15% SDS-PAGE and transferred to a membrane. The same blot was probed sequentially with the following antibodies: anti-H3K36me3 (Active Motif MABI0333), anti-H3K36me2 (Abcam ab9049) and anti-H3K79me3 (GeneTexRM157). Strains analyzed were: pWT XY (PKY4704), K36Q mXmY (PKY4834), P38V_X/K36Q_Y (PKY5140), P38V mXmY (PKY5037).
    2017
    unknown
    Wie komme ich dran?
  9. Detailansicht für Treffer 49 öffnen
    Figure 5. Double H3K36Q mutants fail to repress cryptic promoters. ; (A) Northern blot for STE11 for RNA isolated from the indicated strains, with 25S Northern shown as a loading control. Top band, which migrates at 2.2 kb, represents the full-length STE11 transcript, while the two lower molecular-weight bands correspond to previously-characterized sense transcripts initiating within the STE11 coding region from cryptic promoters (Kaplan et al., 2003). (B) Quantitation of cryptic transcript levels for STE11 in the various strains indicated (n = 3). Levels of cryptic transcripts were normalized to full-length. Average and std. dev. of triplicate measures of these normalized values are graphed on the y-axes. Strains analyzed were: WT wt-c (PKY4701), K36Q wt-c (PKY4827), eaf3Δ WT wt-c (PKY5077), eaf3Δ K36Q wt-c (PKY5079), P38V wt-c (PKY5031), pWT XY (PKY4704), K36Q mXY (PKY4829), K36Q XmY (PKY4831), K36Q mXmY (PKY4834), eaf3Δ pWT XY (PKY5081), eaf3Δ K36Q mXY (PKY5083), eaf3Δ K36Q XmY (PKY5086) and eaf3Δ K36Q mXmY (PKY5087), P38V mXY (PKY5033), P38V XmY (PKY5035), P38V mXmY (PKY5037), K36Q mX/P38V mY (PKY5138), and P38V mX/K36Q mY (PKY5140). pWT_XY, pseudo wild-type; mXY, mutation on X; XmY, mutation on Y; and mXmY, mutation on both X and Y.
    2017
    unknown
    Wie komme ich dran?
  10. Detailansicht für Treffer 50 öffnen
    tidalcycles/Tidal: Ayatakedai ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  11. Detailansicht für Treffer 51 öffnen
    tidalcycles/Tidal: Tunnocks caramel wafer ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  12. Detailansicht für Treffer 52 öffnen
    tidalcycles/Tidal: Dalbeattie ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  13. Detailansicht für Treffer 53 öffnen
    tidalcycles/Tidal: Symonds Yat b ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  14. Detailansicht für Treffer 54 öffnen
    tidalcycles/Tidal: IKLECTIK c ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  15. Detailansicht für Treffer 55 öffnen
    tidalcycles/Tidal: IKLECTIK b ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  16. Detailansicht für Treffer 56 öffnen
    tidalcycles/Tidal: IKLECTIK ...
    McLean, Alex ; Ogborn, David ; et al.
    2021
    academicJournal
    Wie komme ich dran?
  17. Detailansicht für Treffer 57 öffnen
    MXML: Implementation of a web-based application for merging XML documents using XML-SIM
    Viyanon, Waraporn
    In: 2015 13th International Conference on ICT and Knowledge Engineering (ICT & Knowledge Engineering 2015, 2015
    Online Konferenz
    Zugriff:
    Volltext
    Wie komme ich dran?
  18. Detailansicht für Treffer 58 öffnen
    Social network analysis and role hierarchy mining through MXML-based event logs
    Porouhan, Parham ; Premchaiswadi, Wichian
    In: 2015 13th International Conference on ICT and Knowledge Engineering (ICT & Knowledge Engineering 2015, 2015
    Online Konferenz
    Zugriff:
    Volltext
    Wie komme ich dran?
  19. Detailansicht für Treffer 59 öffnen
    tidalcycles/Tidal: We are not DJs ...
    McLean, Alex ; Ogborn, David ; et al.
    2020
    academicJournal
    Wie komme ich dran?
  20. Detailansicht für Treffer 60 öffnen
    tidalcycles/Tidal: Keep live coding live ...
    McLean, Alex ; Ogborn, David ; et al.
    2020
    academicJournal
    Wie komme ich dran?

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